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  • 101.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Hedin, Kerstin
    Handledsdrivna och motoriserade handortoser: en uppföljning1974Report (Other (popular science, discussion, etc.))
  • 102.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. HHJ. Ageing - living conditions and health.
    Heikkinen, R-L
    Depressive symptoms in late life: A comparison of different nordic studies2000In: 15. Nordic Gerontological Congress, Reykjavik, 2000Conference paper (Refereed)
  • 103.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Hofer, S
    Grant, J D
    Twin methodology in longitudinal research on sources of variation in aging and Physical functioning1999In: 5. World Congress on Physical Activity, Aging and Sports, Orlando, 1999Conference paper (Refereed)
  • 104.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Holmgren, Anna-Lena
    Sjukvård i hemmet: En studie bland patienter, anhöriga och personal1984Report (Other (popular science, discussion, etc.))
  • 105.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Jeppson, Lena
    Cognitive functioning and survival in psychogeriatric patients1991In: Acta Psychiatrica Scandinavica, ISSN 0001-690X, E-ISSN 1600-0447, Vol. 84, no 2, p. 160-162Article in journal (Refereed)
  • 106.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Jeppson, Lena
    Val av fel vårdnivå tvingar dementa till onödiga omflyttningar1991In: Läkartidningen, Vol. 88, p. 33-36Article in journal (Refereed)
  • 107.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. HHJ. Ageing - living conditions and health.
    Johansson, Boo
    Att vara äldre än 80: Man klarar sig bra men är lite ensam1989In: Social Forskning, no 1, p. 10-11Article in journal (Refereed)
  • 108.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. HHJ. Ageing - living conditions and health.
    Johansson, Boo
    Det sociala nätverket -en viktig faktor i äldreomsorgen1978In: Socialmedicinsk Tidskrift, Vol. 55, p. 579-583Article in journal (Refereed)
  • 109.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. HHJ. Ageing - living conditions and health.
    Johansson, Boo
    Intelligens och åldrande: Resultat från en svensk longitudinell studie1998In: Tidsskrift for Norsk Psykologforening, p. 768-774Article in journal (Other (popular scientific, debate etc.))
  • 110.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. HHJ. Ageing - living conditions and health.
    Johansson, Boo
    Psykiskt åldrande: Betydelsen av arv och miljö1998In: Tidsskrift for Norsk Psykologforening, Vol. 35, p. 725-730Article in journal (Other (popular scientific, debate etc.))
  • 111.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. HHJ. Ageing - living conditions and health.
    Johansson, Boo
    Psykologisk utveckling: Intelligens och minne1989In: Läkartidningen, Vol. 86, p. 2778-Article in journal (Refereed)
  • 112.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Johansson, Boo
    Malmberg, Bo
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    En studie kring isolering och ensamhet bland äldre1983In: Ensamhet och isolering: rapport från ett seminarium, Jönköping: Institutet för gerontologi, Jönköping , 1983Conference paper (Other academic)
  • 113.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Johansson, Boo
    Malmberg, Bo
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Ensamhet1982In: Nordisk Psykologi: teori, forskning, praksis, ISSN 0029-1463, Vol. 34, no 3, p. 303-311Article in journal (Refereed)
    Abstract [en]

    Social isolation and loneliness are often considered to be important and frequent problems in old age. However, the empirical support for this notion is weak. Results from Swedish studies show that rather extensive social networks continue into old age. Only a small minority can be said to be isolated and suffering from feelings of loneliness. This minority, however, reports a lower life satisfaction, which can also produce physical and psychological problems. Increased attention must be directed toward such negative consequences of weak social networks. This is especially important in discussions of how to alter a social situation characterized by loneliness and isolation. It is emphasized that further research within this field must be based on more explicit theories.

  • 114.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Landahl, Sten
    Psychological functioning in 70- and 75-year-old people: Intellectual functions and cardiovascular disease.1979Report (Other academic)
  • 115.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Landahl, Sten
    Steen, Bertil
    Steen, Gunilla
    SCAG-S: beteendeskattningsskala för geriatriska och psykogeriatriska patienter : en svensk version1980Report (Other (popular science, discussion, etc.))
  • 116.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Landahl, Sten
    Steen, Bertil
    Steen, Gunilla
    Vasopressin of value as a drug in psychogeriatric medicine?: Evaluation of a double blind trial.1981Report (Other (popular science, discussion, etc.))
  • 117.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Malmberg, Bo
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Psykosociala aspekter på personlig hygien1977In: Personlig hygien, Stockholm: Liber , 1977, p. 12-19Chapter in book (Refereed)
  • 118.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Malmberg, Bo
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Socialpsykologiska problemområden i åldrandeprocessen1977Report (Other academic)
  • 119.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Malmberg, Bo
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Äldres flyttningar till service och vårdinstitutioner - erfarenheter från Vetanda kommun1983In: Socialmedicinsk Tidskrift, ISSN 0037-833X, Vol. 60, no 10, p. 539-544Article in journal (Refereed)
  • 120.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Malmberg, Bo
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    McClearn, G
    Pedersen, N L
    A twin register of unlike sexed elderly swedes1995In: The 12th International Twin Congress, Richmond, 1995Conference paper (Refereed)
  • 121.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    McClearn, G E
    Genetic and environmental effects on symptoms of depression in old old twins1997In: World Congress on Psychiatric Genetics, 1997Conference paper (Refereed)
  • 122.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    McClearn, Gerald E
    Lichtenstein, Paul
    Pedersen, Nancy
    Genetic and environmental effects on exercise from early adulthood to old age1995In: Toward healthy aging: international perspectives, Albany, N Y: Center for the Study of Aging , 1995, p. 35-40Chapter in book (Other (popular science, discussion, etc.))
  • 123.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Melin, Else
    Hypnotic susceptibility in old age: Some data from residential homes for old people.1975In: International journal of clinical and experimental hypnosis, ISSN 0020-7144, E-ISSN 1744-5183, Vol. 23, no 3, p. 184-189Article in journal (Refereed)
  • 124.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Melin, Else
    Hypnotiserbarhet hos personer som bor på ålderdomshem samt ett försök till behandling av sömnbesvär med hjälp av suggestioner1973Report (Other (popular science, discussion, etc.))
  • 125.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Mellström, Dan
    Persson, G
    Svanborg, Allvar
    Loneliness in the swedish aged1981In: Journal of Gerontology, ISSN 0022-1422, Vol. 36, no 3, p. 342-349Article in journal (Refereed)
  • 126.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Mårtensson, Ewert
    Åldrandets psykologi1975Book (Other (popular science, discussion, etc.))
  • 127.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. HHJ. Ageing - living conditions and health.
    Mårtensson, Ewert
    Åldrandets psykologi1976In: Psykologisk uppslagsbok, Natur & Kultur, Stockholm , 1976, p. 476-479Chapter in book (Other (popular scientific, debate etc.))
  • 128.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Mårtensson, Ewert
    Malmberg, Bo
    Pensionering: Psykologiska och sociala aspekter1976Book (Other academic)
  • 129.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Nilsson, Lars
    Svanborg, Allvar
    Behavioural and clinical aspects: Longitudinal studies1988In: Psychological assessment of the elderly, London: Churchill Livingstone , 1988, p. 47-60Chapter in book (Other (popular science, discussion, etc.))
  • 130.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Nordqvist, Persy
    Tubbin, Monica
    Arfwidson, Samuel
    Vårdbehov och medicinkonsumtion bland äldre på servicehus med helinackordering: En 14-årsuppföljning1983Report (Other academic)
  • 131.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Norlin, Eva
    Olsson, Agneta
    Psykoterapi och andra metoder vid psykologisk behandling av äldre1974Report (Other academic)
  • 132.
    berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. HHJ. Ageing - living conditions and health.
    Olsson, A
    Psykoterapi inom geriatrik, psykogeriatrik och social åldringsvård1974In: Nordisk Psykologi, Vol. 26, p. 119-128Article in journal (Other (popular scientific, debate etc.))
  • 133.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. HHJ. Ageing - living conditions and health.
    Ruth, Jan-Erik
    Psykogerontologisk forskning om intelligens och kreativitet1982In: Nordisk Psykologi, Vol. 34, p. 275-289Article in journal (Other (popular scientific, debate etc.))
  • 134.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. HHJ. Ageing - living conditions and health.
    Sjöberg, T
    Psykologens roll inom åldringsvården1976In: Socialmedicinsk Tidskrift, Vol. 53, p. 48-52Article in journal (Other (popular scientific, debate etc.))
  • 135.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. HHJ. Ageing - living conditions and health.
    Sjöås Karlsson, K
    Steen, Bertil
    Den fysiska miljön på sjukhem - patienter och personals synpunkter1977In: Sjukhuset,,,, Vol. 54, p. 324-327Article in journal (Other (popular scientific, debate etc.))
  • 136.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. HHJ. Ageing - living conditions and health.
    Steen, G
    Kohortskillnader och intellektuell förmåga1998In: 14. Nordiska kongressen i Gerontologi, Trondheim, 1998Conference paper (Refereed)
  • 137.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Sundström, Gerdt
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Kommunal och regional variation inom äldreomsorgen1989Report (Other (popular scientific, debate etc.))
  • 138.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Svensson, Torbjörn
    An orientation scale for geriatric patients1980In: Age and Ageing, ISSN 0002-0729, E-ISSN 1468-2834, Vol. 9, no 4, p. 215-219Article in journal (Refereed)
  • 139.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. HHJ. Ageing - living conditions and health.
    Svensson, Torbjörn
    En orienteringsskala för geriatriska och psykogeriatriska patienter1978In: Nordisk Psykiatrisk Tidskrift, p. 507-512Article in journal (Other (popular scientific, debate etc.))
  • 140.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. HHJ. Ageing - living conditions and health.
    Svensson, Torbjörn
    Långtidsvård - ett område för förändring1978In: Socialmedicinsk Tidskrift, Vol. 55, p. 585-590Article in journal (Other (popular scientific, debate etc.))
  • 141.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Svensson, Torbjörn
    Skattningsskalor för bedömning av den fysiska miljön hos service- och vårdanläggningar för äldre: BFMÄ-skalan1983Report (Other academic)
  • 142.
    Berg, Stig
    et al.
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Svensson, Torbjörn
    Tjellden, A L
    Milieu treatment in a ward for psychiatric long-term care1977In: Scandinavian journal of social medicine. Supplementum, ISSN 0301-7311, Vol. 14, no Suppl. 14, p. 163-172Article in journal (Refereed)
  • 143. Besga, Ariadna
    et al.
    Cedazo-Minguez, Angel
    Kåreholt, Ingemar
    Jönköping University, School of Health Science, HHJ, Institute of Gerontology.
    Solomon, Alina
    Björkhem, Ingemar
    Winblad, Bengt
    Leoni, Valerio
    Hooshmand, Babak
    Spulber, Gabriela
    Gonzalez-Pinto, Ana
    Kivipelto, Miia
    Wahlund, Lars-Olof
    Differences in brain cholesterol metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms2012In: Neuroscience Letters, ISSN 0304-3940, E-ISSN 1872-7972, Vol. 510, no 2, p. 121-126Article in journal (Refereed)
    Abstract [en]

    Investigate possible associations of white matter hyperintensities (WMHs) with the metabolism of cholesterol and insulin in two subgroups of patients with memory complaints and different CSF Aβ42 and CSF tau levels. 59 patients from the memory clinic at Karolinska Hospital were included. Degree of WMHs was rated using the ARWMC scale and the following biomarkers were measured in CSF and plasma: insulin, cholesterol, lanosterol, lathosterol, and oxidized cholesterol metabolites. The WMHs in CSF control-like group correlated with increased brain cholesterol synthesis and reduced efflux of oxysterols and insulin in CSF. In the CSF AD-like group, the WMHs correlated with increased peripheral cholesterol metabolism. Despite having similar appearance on FLAIR images, the pathogenic mechanisms of WMHS are likely to be different in the two groups investigated.

  • 144.
    Bjursell, Cecilia
    et al.
    Jönköping University, School of Education and Communication, HLK, Lifelong learning/Encell.
    Nystedt, Paul
    Jönköping University, Jönköping International Business School, JIBS, Economics. Jönköping University, School of Health and Welfare, The Jönköping Academy for Improvement of Health and Welfare.
    Björklund, Anita
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Rehabilitation. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    Sternäng, Ola
    Jönköping University, School of Health and Welfare, HHJ, Institute of Gerontology. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping). Stockholm Centre for Health and Social Change (SCOHOS).
    Education level explains participation in work and education later in life2017In: Educational gerontology, ISSN 0360-1277, E-ISSN 1521-0472, Vol. 43, no 10, p. 511-521Article in journal (Refereed)
    Abstract [en]

    A prolonged working life is crucial for sustaining social welfare and fiscal stability for countries facing ageing populations. The group of older adults is not homogeneous; however, differences within the group may affect the propensity to continue working and to participate in continuing education. The aim of this paper is to explore how participation in work and education vary with gender, age, and education level in a sample of older adults. The study was performed in Sweden, a context characterized by high female labour-market-participation rates and a high average retirement age. The participants were 232 members of four of the major senior citizens? organizations. We found no differences in participation in work and education based on gender. People older than 75 years were found to be as active as people 65?75 years old in education, but the older group worked less. There were positive associations between education level and participation in both work and education. Hence, this study implies that socio-economic inequalities along these dimensions are widened later in life. This highlights the importance of engaging workers with lower education levels in educational efforts throughout life. It also emphasizes the need for true lifelong learning in society.

  • 145.
    Bogl, Leonie H.
    et al.
    Institute for Molecular Medicine FIMM, Finland and University of Helsinki, Finland.
    Dahl Aslan, Anna K.
    Jönköping University, School of Health and Welfare, HHJ, Institute of Gerontology. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping). Karolinska Institutet, Sweden.
    Kaprio, Jaakko
    Institute for Molecular Medicine FIMM, Finland and University of Helsinki, Finland.
    Does the sex of one’s co-twin affect height and BMI in adulthood?: A study of dizygotic adult twins from 31 cohorts2017In: Biology of Sex Differences, ISSN 2042-6410, Vol. 8, no 1, article id 14Article in journal (Refereed)
    Abstract [en]

    Background: The comparison of traits in twins from opposite-sex (OS) and same-sex (SS) dizygotic twin pairs is considered a proxy measure of prenatal hormone exposure. To examine possible prenatal hormonal influences on anthropometric traits, we compared mean height, body mass index (BMI) and the prevalence of being overweight or obese between men and women from OS and SS dizygotic twin pairs.

    Methods: The data were derived from COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) database, and included 68,494 SS and 53,808 OS dizygotic twin individuals above the age of 20 years from 31 twin cohorts representing 19 countries. Zygosity was determined by questionnaires or DNA genotyping depending on the study. Multiple regression and logistic regression models adjusted for cohort, age and birth year with the twin type as a predictor were carried out to compare height and BMI in twins from OS pairs with those from SS pairs and to calculate the adjusted odds ratios and 95% confidence intervals for being overweight or obese.

    Results: OS females were, on average, 0.31 cm (95% confidence interval (CI): 0.20, 0.41) taller than SS females. OS males were also, on average, taller than SS males, but this difference was only 0.14 cm (95% CI: 0.02, 0.27). Mean BMI and the prevalence of overweight or obesity did not differ between males and females from SS and OS twin pairs. The statistically significant differences between OS and SS twins for height were small and appeared to reflect our large sample size rather than meaningful differences of public health relevance.

    Conclusions: We found no evidence to support the hypothesis that prenatal hormonal exposure or postnatal socialization (i.e., having grown up with a twin of the opposite sex) has a major impact on height and BMI in adulthood.

  • 146.
    Bokenberger, K.
    et al.
    Karolinska Institutet, Department of Medical Epidemiology & Biostatistics, Stockholm, Sweden.
    Sjölander, A.
    Karolinska Institutet, Department of Medical Epidemiology & Biostatistics, Stockholm, Sweden.
    Dahl Aslan, Anna K.
    Jönköping University, School of Health and Welfare, HHJ, Institute of Gerontology. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping). Karolinska Institutet, Department of Medical Epidemiology & Biostatistics, Stockholm, Sweden.
    Karlsson, Ida K.
    Karolinska Institutet, Department of Medical Epidemiology & Biostatistics, Stockholm, Sweden.
    Akerstedt, T.
    Stockholm University, Stress Research Institute, Stockholm, Sweden.
    Pedersen, N. L.
    Karolinska Institutet, Department of Medical Epidemiology & Biostatistics, Stockholm, Sweden.
    Midlife shift work and risk of incident dementia2017In: Sleep, ISSN 0161-8105, E-ISSN 1550-9109, Vol. 40, p. A425-A425Article in journal (Refereed)
  • 147.
    Bokenberger, Kathleen
    et al.
    Karolinska Institutet.
    Pedersen, Nancy
    Karolinska Institutet.
    Gatz, Margaret
    University of Southern California.
    Dahl, Anna
    Jönköping University, School of Health and Welfare, HHJ. Ageing - living conditions and health. Jönköping University, School of Health and Welfare, HHJ, Institute of Gerontology.
    The Type A behavior pattern and cardiovascular disease as predictors of dementia2014In: Health Psychology, ISSN 0278-6133, E-ISSN 1930-7810, Vol. 33, no 12, p. 1593-1601Article in journal (Refereed)
    Abstract [en]

    Objective: Research has suggested that greater psychophysiological reactivity to stress increases risk of dementia and that those with the Type A behavior pattern (TABP) are predisposed to elevated stress reactivity and cardiovascular disease (CVD), but no study has evaluated the associations among TABP, CVD, and dementia, prospectively. Hence, the present study aimed to investigate dementia risk in relation to TABP and CVD.

    Methods: A population-based cohort of 1,069 persons with a baseline mean age of 64.81 years from the Swedish Twin Registry was followed consecutively for up to 23 years. Based on self-reported items, TABP was measured using 6 scales: Ambition, Stress, Hard-driving, Neuroticism, Cynicism, and Paranoia. CVD was self-reported and dementia was diagnosed adhering to Diagnostic and Statistical Manual of Mental Disorders, third edition, revised (DSM-III-R) or Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) criteria.

    Results: TABP was generally not associated with dementia risk. However, significant interaction effects of stress, paranoia, and cynicism with CVD on dementia risk were observed. That is, for those with CVD, high scores on stress, paranoia, and cynicism were associated with increased risk of dementia (hazard ratio [HR] = 1.43, 95% confidence interval [CI] = 0.95-2.15; HR = 1.39, 95% CI = 0.83-2.33; HR = 1.25, 95% CI = 0.76-2.06, respectively), whereas for those who did not have CVD, high scores on these measures appeared to be protective (HR = 0.76, 95% CI = 0.50-1.14; HR = 0.55, 95% CI = 0.34-0.89; HR = 0.50, 95% CI = 0.29-0.84, respectively).

    Conclusion: Some features of TABP confer an increased risk for dementia in those with CVD, whereas those without CVD are protected. When evaluating the risk of dementia, CVD and personality traits should be taken into consideration.

  • 148.
    Bokenberger, Kathleen
    et al.
    Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden.
    Sjölander, Arvid
    Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden.
    Dahl Aslan, Anna K.
    Jönköping University, School of Health and Welfare, HHJ, Institute of Gerontology. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping). Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden.
    Karlsson, Ida K.
    Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden.
    Åkerstedt, Torbjörn
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
    Pedersen, Nancy Lee
    Department of Psychology, University of Southern California, Los Angeles, United States.
    Shift work and risk of incident dementia: a study of two population-based cohorts2018In: European Journal of Epidemiology, ISSN 0393-2990, E-ISSN 1573-7284, Vol. 33, no 10, p. 977-987Article in journal (Refereed)
    Abstract [en]

    This study aimed to investigate the association between shift work and incident dementia in two population-based cohorts from the Swedish Twin Registry (STR). The STR-1973 sample included 13,283 participants born 1926–1943 who received a mailed questionnaire in 1973 that asked about status (ever/never) and duration (years) of shift work employment. The Screening Across the Lifespan Twin (SALT) sample included 41,199 participants born 1900–1958 who participated in a telephone interview in 1998–2002 that asked about night work status and duration. Dementia diagnoses came from Swedish patient registers. Cox proportional-hazards regression was used to estimate hazard ratios (HR) with 95% confidence intervals (CI). Potential confounders such as age, sex, education, diabetes, cardiovascular disease and stroke were included in adjusted models. In genotyped subsamples (n = 2977 in STR-1973; n = 10,366 in SALT), APOE ε4 status was considered in models. A total of 983 (7.4%) and 1979 (4.8%) dementia cases were identified after a median of 41.2 and 14.1 years follow-up in the STR-1973 and SALT sample, respectively. Ever shift work (HR 1.36, 95% CI 1.15–1.60) and night work (HR 1.12, 95% CI 1.01–1.23) were associated with higher dementia incidence. Modest dose-response associations were observed, where longer duration shift work and night work predicted increased dementia risk. Among APOE ε4 carriers, individuals exposed to ≥ 20 years of shift work and night work had increased dementia risk compared to day workers. Findings indicate that shift work, including night shift work, compared to non-shift jobs is associated with increased dementia incidence. Confirmation of findings is needed. 

  • 149.
    Bokenberger, Kathleen
    et al.
    Karolinska Institutet.
    Ström, Peter
    Karolinska Institutet.
    Aslan, Anna K. Dahl
    Jönköping University, School of Health and Welfare, HHJ, Institute of Gerontology. Karolinska Institutet.
    Johansson, Anna
    Karolinska Institutet.
    Åkerstedt, Torbjörn
    Stockholms universitet.
    Pedersen, Nancy L.
    Karolinska Institutet.
    The effect of shift work on cognitive aging across the late adult life course2015In: The Gerontologist, ISSN 0016-9013, E-ISSN 1758-5341, Vol. 55, article id 360Article in journal (Other academic)
  • 150.
    Bokenberger, Kathleen
    et al.
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
    Ström, Peter
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
    Dahl Aslan, Anna K.
    Jönköping University, School of Health and Welfare, HHJ, Institute of Gerontology. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping). Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
    Johansson, Anna L. V.
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
    Gatz, Margaret
    Department of Psychology, University of Southern California, Los Angeles CA, USA.
    Pedersen, Nancy L.
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
    Åkerstedt, Torbjörn
    Stress Research Institute, Stockholm University, Sweden.
    Association between sleep characteristics and incident dementia accounting for baseline cognitive status: A prospective population-based study2017In: The journals of gerontology. Series A, Biological sciences and medical sciences, ISSN 1079-5006, E-ISSN 1758-535X, Vol. 72, no 1, p. 134-139Article in journal (Refereed)
    Abstract [en]

    Background: While research has shown that sleep disorders are prevalent among people with dementia, the temporal relationship is unclear. We investigated whether atypical sleep characteristics were associated with incident dementia while accounting for baseline cognitive functioning.

    Methods: Screening Across the Lifespan Twin Study (SALT) participants were 11,247 individuals from the Swedish Twin Registry who were at least 65 years at baseline (1998-2002). Sleep and baseline cognitive functioning were assessed via the SALT telephone screening interview. Data on dementia diagnoses came from national health registers. Cox regression was performed to estimate hazard ratios (HR) for dementia.

    Results: After 17 years of follow-up, 1,850 dementia cases were identified. Short (≤ 6 hours) and extended (> 9 hours) time-in-bed (TIB) compared to the middle reference group (HR=1.40, 95% CI=1.06-1.85, HR=1.11, 95% CI=1.00-1.24, respectively) and rising at 8:00AM or later compared to earlier rising (HR=1.12, 95% CI=1.01-1.24) were associated with higher dementia incidence. Bedtime, sleep quality, restorative sleep, and heavy snoring were not significant predictors. Findings stratified by baseline cognitive status indicated that the association between short TIB and dementia remained in those cognitively intact at the start.

    Conclusions: Short and extended TIB as well as delayed rising among older adults predicted increased dementia incidence in the following 17 years. The pattern of findings suggests that extended TIB and late rising represent prodromal features whereas short TIB appeared to be a risk factor for dementia.

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