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  • 1.
    Andersson, Emma
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Lindh, Andréa
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Jämförelse mellan konventionell utstryksmetod och vätskebaserad ThinPrepmetod vid preparering av etanolfixerade exsudat2018Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Preparation of effusions for cytological evaluation can be performed with different methods. Conventional smears are performed by spreading the sample directly onto a slide while liquid-based ThinPrep method prepares the sample in an automated process. The aim of this study was to compare conventional smears with liquid-based ThinPrep preparation, with additional acetic acid, of effusions fixated with ethanol. A total of 34 samples of pleural effusions and ascites were included. The samples were prepared with conventional smears and two versions of the ThinPrep method, ThinPrep method 1 and ThinPrep method 2. The preparations were examined by two cytotechnologists based on five criteria; occurrence of cells, occurrence of inflammatory cells, cell morphology, background material and the presence of atypical or malignant cells. The results showed that ThinPrep method 2 obtained equivalent and, in some aspects, even better results compared to conventional smears. In general, the ThinPrep method has several advantages compared to the conventional smears. In particular, it is timesaving when examining the slides, which also benefits the patients. A more comprehensive study is recommended to confirm the results of this study.

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