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  • 1.
    Abbas, Ali
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine.
    Påverkan av koffein på blodtryck, flödeshastighet och lumendiameter i arteria carotis communis: En ultraljudsundersökning inom klinisk fysiologi2022Independent thesis Basic level (university diploma), 180 HE creditsStudent thesis
    Abstract [sv]

    Ultraljudsundersökningar av arteria carotis communis (CCA) utförs med ultraljud vid bedömning av kärlförändringar och flödeshastigheter (FH) samt utredning av sjukdomar i CCA. Lumendiameter (LD) i CCA är en markör för riskfaktorer som leder till stroke, hjärtinfarkt och ateroskleros. Syftet med den aktuella studien är att studera om det sker någon vasoaktiv förändring i CCA vid konsumtion av koffein hos unga vuxna. Det var 33 försökspersoner som delades upp i grupper beroende på deras koffeinkonsumtionsvanor och undersöktes med ultraljud. Försökspersonerna hade innan undersökning inte konsumerat koffein på 12 timmar. Undersökningen utfördes innan konsumtion av koffeindryck och 45 minuter efter koffeinkonsumtion. En signifikant skillnad efter konsumtion av koffein påvisades i lågkonsument gruppen (grupp 1) (p.0,06) och högkonsument gruppen (grupp 3) (p=0,05). En positiv korrelation mellan LD innan och efter konsumtion (r=0,955; p <0,01) samt FH innan och efter konsumtion (r=0,393; p <0,01) av koffein kunde påvisas.

    Nyckelord: Carotisduplex, Kaffe, Vasoaktiv, CCA.

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  • 2.
    Abbas, Hassan
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Huzeirovic, Melisa
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    En jämförelse mellan två sjukdomsgrupper med PET/CT som undersökningsmetod: Beräkning av den totala effektiva dosen från PET- och CT-undersökning2019Independent thesis Basic level (degree of Bachelor), 180 HE creditsStudent thesis
    Abstract [en]

    Background: Lung cancer and malignant melanoma are diseases investigated by the dual-modality positron emission tomography/computed tomography (PET/CT). There are radiation risks with the examination that can appear as stochastic effects such as cancer. The aim of this study was to compare the radiation doses between the lung cancer group (suspected or verified) and the malignant melanoma group by calculating the total effective radiation dose and to declare the risk with the PET/CT examination. Material and method: The material contained parameters regarding the examination and the sample contained 20 patients from the two groups. The method was retrospective with a quantitative approach. Results: There was a significant difference (p <0,001) between these two groups, were the lung cancer group received 11,95 milliSievert (mSv) and the malignant melanoma group 6,03 mSv and the percentage risk for lethal cancer increased by 0,06% and 0,03%, respectively. Conclusions: The lung cancer group received twice as much effective dose than the malignant melanoma group. However, the effective dose is so low that the risk increase of the lethal cancer is marginal, and the benefit of the examination outweighs the risks.

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  • 3.
    Abiib, Mulki
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Cvetkovic, Anna
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Utvärdering av instrumentet UF-5000 för automatiserad urinpartikelanalys i en metodjämförelse med manuell mikroskopering av urinsediment2018Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Introduction: Microscopy is gold standard for urine sediment analysis, although the method is often insufficiently standardized. Several automated instruments, such as UF-5000, are commercially available on the market. Urine sediment analysis is crucial for diagnosis of kidney and urinary tract diseases where elements such as erythrocytes, leukocytes, epithelial cells, casts and crystals can be identified. Aim: The aim was to evaluate the performance of UF-5000 and compare the method with manual microscopic analysis of urine sediment. Method: Analysis with UF-5000 and microscopy was conducted on 69 samples. Data were processed with Passing Bablok-regression, Bland-Altman bias plot and Spearman's rank order correlation. Result: Comparison showed statistical significance between the two methods. Performance evaluation showed high accuracy apart from the coefficient of variation for low concentration of leukocytes and systematic error for linearity. Discussion: Since microscopy of urine sediment is an insufficiently standardized method, differences were acknowledged caused by discrepancies in the reference method. Further studies where UF-5000 is compared to a more standardized manual microscopy with a larger amount of pathological urine samples is of great importance. Reduction for cut-off may also be relevant. For further analysis of linearity, an additional instrument should be used as a complement.

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  • 4.
    Abrahamsson, Agneta
    et al.
    Jönköping University, School of Health and Welfare. University College of Kristianstad,Kristianstad.
    Lindmark, Ulrika
    Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine.
    Gerdner, Arne
    Jönköping University, School of Health and Welfare, HHJ. SALVE (Social challenges, Actors, Living conditions, reseach VEnue). Jönköping University, School of Health and Welfare, HHJ, Dept. of Rehabilitation.
    Sense of coherence of reindeer herders and other Samis in comparison to other Swedish citizens2013In: International Journal of Circumpolar Health, ISSN 1239-9736, E-ISSN 2242-3982, Vol. 72, p. -20633Article in journal (Refereed)
    Abstract [en]

    Background. Samis are indigenous people in north Europe. In the territory called Sa´pmi (Lapland), reindeer herding is the traditional base for the Sami economy. The relation between living conditions and positive health of the Swedish Samis has been sparsely studied. As health is closely linked to sense of coherence (SOC), an understanding of the background factors to SOC may contribute knowledge that might be useful in promoting living conditions and health.

    Methods. The study examines relations between the level of SOC and background factors from surveys in a Sami population (n=613) in comparison to a non-Sami population (n=525) in Sweden, and in comparison between 2 subsamples of Samis, that is, herders and non-herders.

    Results. There are more similarities than differences between the Sami and non-Sami populations. However, dividing the Sami population, reindeer herders had significantly lower SOC, and in specific the subcomponent manageability, that is, less ability to use available resources to meet different demands in life, compared to non-herders.

    Conclusions. In addition to age and health, predictors of SOC are related to the life form of reindeer husbandry and the belonging to the herding community

  • 5. Abrahamsson, K H
    et al.
    Berggren, U
    Hakeberg, Magnus
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Oral health.
    Carlsson, S G
    Phobic avoidance and regular dental care in fearful dental patients: a comparative study.2001In: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 59, no 5, p. 273-279Article in journal (Refereed)
  • 6. Abrahamsson, K H
    et al.
    Stenman, J
    Ohrn, K
    Hakeberg, Magnus
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Oral health.
    Attitudes to dental hygienists: evaluation of the Dental Hygienist Beliefs Survey in a Swedish population of patients and students.2007In: International Journal of Dental Hygiene, ISSN 1601-5029, E-ISSN 1601-5037, Vol. 5, no 2, p. 95-102Article in journal (Refereed)
    Abstract [en]

    The aim was to evaluate and test the psychometric properties of the Dental Hygienist Beliefs Survey (DHBS) in a Swedish sample of different patient groups and students. It was hypothesized that negative dental hygienist beliefs would discriminate between fearful and non-fearful study groups. The DHBS was distributed together with the revised Dental Beliefs Survey (DBS-R) and the Dental Anxiety Scale (DAS). The study sample included 394 subjects (130 students, 144 general dental patients, 90 periodontal patients and 30 patients on a waiting list for dental fear treatment). The results verified that the DHBS discriminates well between dentally fearful and non-fearful study groups. The DHBS had high internal consistency (Cronbach's alpha = 0.96-0.98) in all the groups. The correlation between the DHBS and the DBS-R was high (rho = 0.82, P < 0.001). Furthermore, the DHBS correlated significantly with the DAS, as well as with a low but significant correlation to age (more negative attitudes in younger age groups) and gender (more negative attitudes amongst women). Regression analysis showed that gender and the DHBS items: 23, 16 and 28, i.e. items related to feeling helpless, worries/fears not being taken seriously and fear about 'bad news' possibly preventing treatment, were the most important predictors of dental fear. The results suggest that the DHBS may be a valid and reliable scale to use in order to assess patient's specific attitudes to dental hygienists. However, the psychometric properties including test-retest analysis and the underlying factor structure of the DHBS need to be further explored.

  • 7. Abrahamsson, Kajsa H
    et al.
    Hakeberg, Magnus
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Oral health.
    Stenman, Jane
    Ohrn, Kerstin
    Dental beliefs: evaluation of the Swedish version of the revised Dental Beliefs Survey in different patient groups and in a non-clinical student sample.2006In: European Journal of Oral Sciences, ISSN 0909-8836, E-ISSN 1600-0722, Vol. 114, no 3, p. 209-215Article in journal (Refereed)
    Abstract [en]

    The aim of this study was to evaluate and to test the psychometric properties of a Swedish version of the revised Dental Beliefs Survey (DBS-R) in different patient groups and in a non-clinical sample of students. It was hypothesized that negative dental beliefs, assessed using the DBS-R, would discriminate between fearful and non-fearful study groups. The questionnaire was distributed together with the Dental Anxiety Scale (DAS). The sample included 550 adults who responded to the questionnaires (206 students, 177 general dental patients, 105 periodontal patients and 62 patients at a waiting list for dental-fear treatment). The internal drop-out rate was low. The results confirmed that the DBS-R discriminates well between fearful patients and the other study groups. The DBS-R had a high internal consistency in all the study groups. Furthermore, the DBS-R correlated significantly with age (higher values in younger age groups) and the DAS. Regression analyses showed that the DBS-R subdimensions of 'communication' and 'control'/or 'trust', respectively, were significant predictors for dental fear. The results suggest that the DBS-R is a reliable and valid instrument for use in different Swedish patient- and non-clinical population groups in order to assess attitudes to dentists. However, the underlying factor structure of the DBS-R needs to be further explored and established.

  • 8. Abrahamsson, Kajsa Henning
    et al.
    Berggren, Ulf
    Hakeberg, Magnus
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Oral health.
    Carlsson, Sven G
    The importance of dental beliefs for the outcome of dental-fear treatment.2003In: European Journal of Oral Sciences, ISSN 0909-8836, E-ISSN 1600-0722, Vol. 111, no 2, p. 99-105Article in journal (Refereed)
  • 9.
    Abuaita, Areej
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    El Saleh, Asmaa
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Utvärdering av analysmetod för bestämning av anti-FXa aktivitet i plasma hos patienter behandlade med apixaban eller LMH2019Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Introduction: Apixaban and low molecular weight heparin (LMWH), are anticoagulants that prevent clot formation by inhibiting factor Xa. Increasingly more patients use apixaban and LMWH, for this reason the laboratory medicine at the county hospital Ryhov needs to evaluate methods of analysis for apixaban and LMWH to be able to implement the analyzes in clinical routine. Aim: The purpose of the study was to evaluate the assay method for determining anti-FXa activity in plasma in patients treated with apixaban or LMWH using chromogenic substrate method. Method: The method evaluation consisted of four steps: repeatability, intermediate precision measures, compliance with validated method and analysis of normal population. The evaluation was performed using Sysmex CS-2100 where 20 respective 40 patient samples were analyzed for apixaban and LMWH as well as 10 normal population samples. Factor Xa activity was quantitatively determined using light absorption at 405 nm.Result and discussion: Repeatability and intermediate precision showed low CV. Patient samples showed consistent results with reference values from other laboratories where r2 for apixaban and LMWH were 0.95. Deviant results may be due to measurement errors or confusion between samples. Analysis of normal population showed that values were below the lowest reliable value. Conclusion: Evaluation of the analysis method apixaban and LMWH at Ryhov's laboratory showed good results, which confirms that the assay method can be used in clinical routine.

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  • 10. Adiels, Anne-Marie
    et al.
    Helkimo, Martti
    Magnusson, Tomas
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Oral health.
    Tactile stimulation as a complementary treatment of temporomandibular disorders in patients with fibromyalgia syndrome: A pilot study.2005In: Swedish Dental Journal, ISSN 0347-9994, Vol. 29, no 1, p. 17-25Article in journal (Refereed)
  • 11.
    Agid, Nyroz
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Sjöqvist, Evelina
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Prevalence of hookworm infection evaluated with Willis flotation and Formal Ethyl Acetate concentration: A field study in Da Nang, Vietnam2016Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Hookworm infection can cause nausea, stomach pain and anemia, with the most harmful effect being found among women of reproductive age and children. The infection rates is high in poor parts of the world with a high number of infected in Asia. The infection is many times neglected since it rarely causes mortality, however the morbidity can be destructive. In Vietnam the prevalence of hookworm is largely unknown, but there is believed to be a 29-80 % infection rate in the country. Through a field study in Da Nang, Vietnam, the prevalence of hookworm was identified using two methods, Willis flotation and formal ethyl acetate concentration. Any correlation between hookworm infection and individuals’ gender, age and geographic area was evaluated. A total of 101 consecutive selected samples from hospitals and communities in rural and urban parts of the city were obtained from both gender ranging between 1-72 years in age. No quantitative differences were found between the two methods nor any correlation between genders (p-value 0,143). The overall prevalence was 16,8%. The rural part of the city showed a higher infection rate in contrast to the urban districts (p-value 0,001). Individuals in the age group 25-48 showed a higher infection rate in contrast to the other age groups (p-value 0,035). 

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  • 12.
    Ahlander, Britt-Marie
    et al.
    Department of Radiology, Ryhov County Hospital, Jönköping, Sweden.
    Maret, Eva
    Department of Radiology, Ryhov County Hospital, Jönköping, Sweden.
    Brudin, Lars
    Department of Clinical Physiology, Kalmar County Hospital, Kalmar, Sweden.
    Starck, Sven-Åke
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine. Department of Oncology, Hospital Physics, Ryhov County Hospital, Jönköping, Sweden.
    Engvall, Jan
    Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.
    An echo-planar imaging sequence is superior to a steady-state free precession sequence for visual as well as quantitative assessment of cardiac magnetic resonance stress perfusion2017In: Clinical Physiology and Functional Imaging, ISSN 1475-0961, E-ISSN 1475-097X, Vol. 37, no 1, p. 52-61Article in journal (Refereed)
    Abstract [en]

    Background: To assess myocardial perfusion, steady-state free precession cardiac magnetic resonance (SSFP, CMR) was compared with gradient-echo–echo-planar imaging (GRE-EPI) using myocardial perfusion scintigraphy (MPS) as reference.

    Methods: Cardiac magnetic resonance perfusion was recorded in 30 patients with SSFP and in another 30 patients with GRE-EPI. Timing and extent of inflow delay to the myocardium was visually assessed. Signal-to-noise (SNR) and contrast-to-noise (CNR) ratios were calculated. Myocardial scar was visualized with a phase-sensitive inversion recovery sequence (PSIR). All scar positive segments were considered pathologic. In MPS, stress and rest images were used as in clinical reporting. The CMR contrast wash-in slope was calculated and compared with the stress score from the MPS examination. CMR scar, CMR perfusion and MPS were assessed separately by one expert for each method who was blinded to other aspects of the study.

    Results: Visual assessment of CMR had a sensitivity for the detection of an abnormal MPS at 78% (SSFP) versus 91% (GRE-EPI) and a specificity of 58% (SSFP) versus 84% (GRE-EPI). Kappa statistics for SSFP and MPS was 0·29, for GRE-EPI and MPS 0·72. The ANOVA of CMR perfusion slopes for all segments versus MPS score (four levels based on MPS) had correlation r = 0·64 (SSFP) and r = 0·96 (GRE-EPI). SNR was for normal segments 35·63 ± 11·80 (SSFP) and 17·98 ± 8·31 (GRE-EPI), while CNR was 28·79 ± 10·43 (SSFP) and 13·06 ± 7·61 (GRE-EPI).

    Conclusion: GRE-EPI displayed higher agreement with the MPS results than SSFP despite significantly lower signal intensity, SNR and CNR.

  • 13. Ahlqwist, M
    et al.
    Bengtsson, C
    Hakeberg, Magnus
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Oral health.
    Hägglin, C
    Dental status of women in a 24-year longitudinal and cross-sectional study: Results from a population study of women in Göteborg.1999In: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 57, no 3, p. 162-167Article in journal (Refereed)
  • 14.
    Ahlstrand, Inger
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Rehabilitation. Jönköping University, School of Health and Welfare, HHJ. ADULT.
    Larsson, Ingrid
    School of Health and Welfare, Halmstad University, Halmstad, Sweden.
    Larsson, Margaretha
    School of Health and Education, University of Skövde, Skövde, Sweden.
    Ekman, Aimée
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Social Work. Jönköping University, School of Health and Welfare, HHJ. SALVE (Social challenges, Actors, Living conditions, reseach VEnue). Jönköping University, School of Health and Welfare, HHJ. ADULT.
    Hedén, Lena
    Faculty of Caring Science, Work Life and Social Welfare, University of Borås, Borås, Sweden.
    Laakso, Katja
    Institute of Health and Care Sciences, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
    Lindmark, Ulrika
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping). Department of Health Sciences, Karlstad University, Karlstad, Sweden.
    Nunstedt, Håkan
    Department of Health Sciences, University West, Trollhättan, Sweden.
    Oxelmark, Lena
    Institute of Health and Care Sciences, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
    Pennbrant, Sandra
    Department of Health Sciences, University West, Trollhättan, Sweden.
    Sundler, Annelie J.
    Faculty of Caring Science, Work Life and Social Welfare, University of Borås, Borås, Sweden.
    Hallgren, Jenny
    School of Health and Education, University of Skövde, Skövde, Sweden.
    Health-promoting factors among students in higher education within health care and social work: a cross-sectional analysis of baseline data in a multicentre longitudinal study2022In: BMC Public Health, E-ISSN 1471-2458, Vol. 22, no 1, article id 1314Article in journal (Refereed)
    Abstract [en]

    Background: Educational environments are considered important in strengthening students’ health status and knowledge, which are associated with good educational outcomes. It has been suggested to establish healthy universities based on a salutogenic approach – namely, health promotion. The aim of this study was to describe health-promoting resources and factors among first-semester students in higher education in healthcare and social work.

    Methods: This cross-sectional study is based on a survey distributed among all students in seven healthcare and social work programmes at six universities in southern Sweden. The survey was carried out in 2018 using a self-reported, web-based questionnaire focussing on general health and well-being, lifestyle factors together with three validated instruments measuring health-promoting factors and processes: the Sense of Coherence (SOC) scale, Salutogenic Health Indicator Scale (SHIS) and Occupational Balance Questionnaire (OBQ).

    Results: Of 2283 students, 851 (37.3%) completed the survey, of whom 742 (87.1%) were women; 722 (84.8%) were enrolled on healthcare programmes, and 129 (15.2%) were enrolled on social work programmes. Most reported good general health and well-being (88.1% and 83.7%, respectively). The total mean scores for the SOC scale, SHIS and OBQ were, respectively, 59.09 (SD = 11.78), 44.04 (SD = 9.38) and 26.40 (SD = 7.07). Well-being and several healthy lifestyles were related to better general health and higher SOC, SHIS and OBQ scores. Multiple linear and logistic regressions showed that perceived well-being and no sleeping problems significantly predicted higher general health and higher SOC, SHIS and OBQ scores. Being less sedentary and non-smoking habits were significant predictors of higher SOC.

    Conclusions: Swedish students in higher education within the healthcare and social work sector report good general health and well-being in the first semester, as well as health-promoting resources (i.e. SOC, SHIS and OBQ), and in some aspects, a healthy lifestyle. High-intensity exercise, no sleeping problems and non-smoking seem to be of importance to both general health and health-promotive resources. This study contributes to knowledge about the health promotive characteristics of students in the healthcare and social work fields, which is of importance for planning universities with a salutogenic approach.

  • 15.
    Ahonen, Hanna
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Odontology and Oral Health Science. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health.
    Broström, Anders
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Nursing Science. Jönköping University, School of Health and Welfare, HHJ. ADULT. Univ Hosp Linkoping, Dept Clin Neurophysiol, Linkoping, Sweden..
    Fransson, Eleonor I.
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping). Jonkoping Univ, Sch Hlth & Welf, ADULT, Jonkoping, Sweden..
    Neher, Margit
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Rehabilitation. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, The Jönköping Academy for Improvement of Health and Welfare.
    Lindmark, Ulrika
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping). Karlstad Univ, Dept Hlth Sci, Karlstad, Sweden..
    Oral health-related situations among patients with experience of continuous positive airway pressure treatment: a critical incident analysis of experiences and actions2022In: Journal of Sleep Research, ISSN 0962-1105, E-ISSN 1365-2869, Vol. 31, no Suppl 1, article id P085Article in journal (Refereed)
  • 16.
    Ahonen, Hanna
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Odontology and Oral Health Science. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health.
    Broström, Anders
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Nursing Science. Jönköping University, School of Health and Welfare, HHJ. ADULT. Department of Clinical Neurophysiology, University Hospital Linköping, Linköping, Sweden.
    Fransson, Eleonor I.
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    Neher, Margit
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Rehabilitation. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, The Jönköping Academy for Improvement of Health and Welfare.
    Lindmark, Ulrika
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Department of Health Sciences, Karlstad University, Karlstad, Sweden.
    “The terrible dryness woke me up, I had some trouble breathing”- critical situations related to oral health as described by CPAP-treated persons with obstructive sleep apnea2022In: Journal of Sleep Research, ISSN 0962-1105, E-ISSN 1365-2869, Vol. 31, no 6, article id e13670Article in journal (Refereed)
    Abstract [en]

    Continuous positive airway pressure is a common and effective treatment for obstructive sleep apnea, but adherence remains an issue. Both obstructive sleep apnea and oral diseases are associated with cardiovascular diseases, and as oral dryness contributes to treatment abandonment, oral health is of importance for this patient group. The aim was therefore to explore how persons with continuous positive airway pressure-treated obstructive sleep apnea experience situations associated with their oral health, and which actions they take to manage these. An explorative and descriptive design was adopted using the critical incident technique. Based on a purposeful selection, 18 adults with long-term experience of continuous positive airway pressure-treatment were interviewed using a semi-structured interview guide. Both negative and positive situations were described. Negative situations consisted of challenges with breathing, including mouth-breathing, choking sensations, problems with night-time and daytime oral dryness, changes in the saliva composition, and deteriorating oral health. Positive situations included experiences of reduced mouth-breathing and oral dryness. The situations were often successfully managed by mimicking daytime movements, changing sleeping position, adjusting the CPAP-device and mask, increasing oral hygiene efforts, drinking water, using a humidifier or chinstrap, or contacting their oral healthcare clinic. Long-term experience of persons with continuous positive airway pressure-treated obstructive sleep apnea regard situations and actions from everyday life. Successful management can contribute to long-term adherence and decrease negative effects on oral health. More interdisciplinary collaborations could enable identification and adequate recommendations for persons who experience negative situations during their continuous positive airway pressure treatment.

  • 17.
    Ahonen, Hanna
    et al.
    Jönköping University, School of Health and Welfare, HHJ. ADULT.
    Kvarnvik, Christine
    Folktandvården Region Jönköpings län.
    Broström, Anders
    Jönköping University, School of Health and Welfare, HHJ, Department of Nursing Science. Jönköping University, School of Health and Welfare, HHJ. ADULT. Avdelningen för Klinisk Neurofysiologi, Linköpings Universitetssjukhus, Linköping.
    Fransson, Eleonor I.
    Jönköping University, School of Health and Welfare, HHJ, Department of Clinical Diagnostics. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping). Jönköping University, School of Health and Welfare, HHJ, Institute of Gerontology. Inspektionen för Socialförsäkringen, Göteborg.
    Nygårdh, Annette
    Jönköping University, School of Health and Welfare, HHJ, Department of Nursing Science. Jönköping University, School of Health and Welfare, The Jönköping Academy for Improvement of Health and Welfare. Jönköping University, School of Health and Welfare, HHJ. IMPROVE (Improvement, innovation, and leadership in health and welfare).
    Stensson, Malin
    Jönköping University, School of Health and Welfare, HHJ, Department of Clinical Diagnostics. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Jönköping University, School of Health and Welfare, HHJ. CHILD. Jönköping University, School of Health and Welfare, HHJ. Biomedical Platform.
    Lindmark, Ulrika
    Jönköping University, School of Health and Welfare, HHJ, Department of Clinical Diagnostics. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    Oral hälsa och obstruktiv sömnapné- protokoll för en longitudinell studie2019Conference paper (Refereed)
  • 18.
    Ahonen, Hanna
    et al.
    Jönköping University, School of Health and Welfare, HHJ. ADULT.
    Kvarnvik, Christine
    Broström, Anders
    Jönköping University, School of Health and Welfare, HHJ, Department of Nursing Science. Jönköping University, School of Health and Welfare, HHJ. ADULT.
    Fransson, Eleonor I.
    Jönköping University, School of Health and Welfare, HHJ, Department of Clinical Diagnostics. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping). Jönköping University, School of Health and Welfare, HHJ, Institute of Gerontology.
    Nygårdh, Annette
    Jönköping University, School of Health and Welfare, HHJ, Department of Nursing Science. Jönköping University, School of Health and Welfare, The Jönköping Academy for Improvement of Health and Welfare. Jönköping University, School of Health and Welfare, HHJ. IMPROVE (Improvement, innovation, and leadership in health and welfare).
    Stensson, Malin
    Jönköping University, School of Health and Welfare, HHJ, Department of Clinical Diagnostics. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Jönköping University, School of Health and Welfare, HHJ. CHILD. Jönköping University, School of Health and Welfare, HHJ. Biomedical Platform.
    Norderyd, Ola
    Jönköping University, School of Health and Welfare, HHJ, Department of Clinical Diagnostics.
    Ulander, Martin
    Sunnergren, Ola
    Jansson, Henrik
    Sayardoust, Shariel
    Lindmark, Ulrika
    Jönköping University, School of Health and Welfare, HHJ, Department of Clinical Diagnostics. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    “No one seems to know”: Studieprotokoll för utvärdering av ett teoretiskt ramverk för oral hälsa avseende reliabilitet och validitet i en obstruktiv sömnapné population2019Conference paper (Other academic)
  • 19.
    Ahonen, Hanna
    et al.
    Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health.
    Kvarnvik, Christine
    Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. The Institute for Postgraduate Dental Education, Region Jönköping County, Jönköping, Sweden; Department of Endodontics, Periodontology and Prosthetics, Public Dental Health, Jönköping County Council, Jönköping, Sweden.
    Norderyd, Ola
    The Institute for Postgraduate Dental Education, Region Jönköping County, Jönköping, Sweden; Department of Endodontics, Periodontology and Prosthetics, Public Dental Health, Jönköping County Council, Jönköping, Sweden; Faculty of Odontology, Malmö University, Malmö, Sweden.
    Broström, Anders
    Jönköping University, School of Health and Welfare, HHJ, Department of Nursing Science. Jönköping University, School of Health and Welfare, HHJ. ADULT. Department of Clinical Neurophysiology, University Hospital Linköping, Linköping, Sweden.
    Fransson, Eleonor I.
    Jönköping University, School of Health and Welfare, HHJ, Department of Clinical Diagnostics. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Jönköping University, School of Health and Welfare, HHJ. ADULT.
    Lindmark, Ulrika
    Jönköping University, School of Health and Welfare, HHJ, Department of Clinical Diagnostics. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    Clinical and self-reported measurements to be included in the core elements of the World Dental Federation's theoretical framework of oral health2021In: International Dental Journal, ISSN 0020-6539, E-ISSN 1875-595X, Vol. 71, no 1, p. 53-62Article in journal (Refereed)
    Abstract [en]

    Introduction

    Oral health is part of general health, and oral diseases share risk factors with several non-communicable diseases. The World Dental Federation (FDI) has published a theoretical framework illustrating the complex interactions between the core elements of oral health (CEOHs): driving determinants, moderating factors, and general health and well-being. However, the framework does not specify which self-reported or clinical measurements to be included in the CEOHs.

    Objectives

    To explore oral health measurements relevant for a general adult population to be included in the CEOHs in the FDI's theoretical framework of oral health.

    Materials and methods

    A psychometric study was performed, using cross-sectional data from Sweden (= 630, 54% women, mean age 49.7 years). The data set initially consisted of 186 self-reported and clinical measurements. To identify suitable measurements, the selection was discussed in different settings, including both experts and patients. Principal component analyses (PCAs) were performed to explore, reduce and evaluate measurements to be included in the three CEOHs. Internal consistency was estimated by Cronbach's Alpha.

    Results

    The validation process yielded 13 measurements (four clinical, nine self-reported) in concordance with the CEOHs. PCAs confirmed robust validity regarding the construction, predicting 60.85% of variance, representing psychosocial function (number of measurements = 5), disease and condition status (number of measurements = 4), and physiological function (number of measurements = 4). Cronbach's Alpha indicated good to sufficient internal consistency for each component in the constructs (a = 0.88, 0.68, 0.61, respectively).

    Conclusion

    In a Swedish general adult population, 13 self-reported and clinical measurements can be relevant to include to operationalise CEOHs in the FDI's theoretical framework.

  • 20.
    Ahonen, Hanna
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Odontology and Oral Health Science. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health.
    Neher, Margit
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Rehabilitation. Jönköping University, School of Health and Welfare, HHJ. ADULT.
    Fransson, Eleonor I.
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    Broström, Anders
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Nursing Science. Jönköping University, School of Health and Welfare, HHJ. ADULT. Department of Clinical Neurophysiology, University Hospital Linköping, Linköping, Sweden.
    Lindmark, Ulrika
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Department of Health Sciences, Karlstad University, Karlstad, Sweden.
    Views about oral health determinants as described by persons with continuous positive airway pressure-treated obstructive sleep apnea: A qualitative studyManuscript (preprint) (Other academic)
  • 21.
    Ahonen, Hanna
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Department of Odontology and Oral Health Science. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health.
    Neher, Margit
    Jönköping University, School of Health and Welfare, HHJ, Department of Rehabilitation. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, The Jönköping Academy for Improvement of Health and Welfare.
    Fransson, Eleonor I.
    Jönköping University, School of Health and Welfare, HHJ, Department of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    Broström, Anders
    Jönköping University, School of Health and Welfare, HHJ, Department of Nursing Science. Jönköping University, School of Health and Welfare, HHJ. ADULT. Department of Clinical Neurophysiology, University Hospital Linköping, Linköping, Sweden.
    Lindmark, Ulrika
    Jönköping University, School of Health and Welfare, HHJ, Department of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping). Department of Health Sciences, Karlstad University, Karlstad, Sweden.
    Views on oral health determinants as described by persons with continuous positive airway pressure-treated obstructive sleep apnoea: a qualitative study2023In: BMC Oral Health, ISSN 1472-6831, E-ISSN 1472-6831, Vol. 23, no 1, article id 407Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: Oral diseases have been associated with cardiovascular diseases, and persons with continuous positive airway pressure [CPAP]-treated obstructive sleep apnoea [OSA] have an increased risk for negative consequences for both oral and general health. CPAP treatment is often life-long and adherence to treatment is essential. Xerostomia is a common side-effect which can lead to treatment abandonment. Oral health is a changeable part of our general health and well-being and exploring the views of oral health determinants from persons with experience of CPAP-treatment is important to prevent adverse oral health outcomes. The purpose of this study was to explore what persons with experience of CPAP-treated OSA view as determinants for their oral health.

    METHODS: Eighteen persons with long-term experience of CPAP-treated OSA were purposively selected. Data were collected by semi-structured individual interviews. A code book based on the World Dental Federation's [FDI] theoretical framework for oral health was developed and used to analyse the data using directed content analysis. The domains in the framework's component driving determinants were used as pre-determined categories. Using the description of driving determinants as a guide, meaning units were extracted from the interview transcripts through an inductive approach. Then, by employing a deductive approach the code book was used to categorise the meaning units into the pre-determined categories.

    FINDINGS: The views on oral health determinants described by the informants were compatible with the five domains in the component driving determinants in the FDI's theoretical framework. Ageing, heredity, and salivation (biological and genetic factors), influences from family and the wider society (social environment), location and re-localisation (physical environment), oral hygiene habits, motivation, willingness to change, professional support (health behaviours), and availability, control, finances, and trust (access to care) were viewed as important oral health determinants by the informants.

    CONCLUSION: The study points to a variety of individual oral health-related experiences that oral healthcare professionals could consider when designing interventions to reduce xerostomia and prevent adverse oral health outcomes for persons undergoing long-term CPAP-treatment.

  • 22.
    Ahonen, Hanna
    et al.
    Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health.
    Pakpour, Amir H.
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Nursing Science.
    Norderyd, Ola
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine.
    Broström, Anders
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Nursing Science. Jönköping University, School of Health and Welfare, HHJ. ADULT.
    Fransson, Eleonor I.
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    Lindmark, Ulrika
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    Applying World Dental Federation Theoretical Framework for Oral Health in a General Population2022In: International Dental Journal, ISSN 0020-6539, E-ISSN 1875-595X, Vol. 72, no 4, p. 536-544Article in journal (Refereed)
    Abstract [en]

    Introduction: The World Dental Federation (FDI) has recently proposed a new definition and theoretical framework of oral health. The theoretical framework includes 4 main components and describes the relationships amongst them. In 2020, an international work group proposed the minimum Adult Oral Health Standard Set (AOHSS) of variables to measure oral health, which was mapped onto the FDI's theoretical framework. By using an empirical data set, the proposed variables in the AOHSS and the potential interactions amongst the components of the FDI's theoretical framework can be tested. The purpose of this research was to investigate structural relations of the components of the FDI's theoretical framework of oral health based on data from a general adult population.

    Methods: Data from a previously conducted Swedish cross-sectional study focusing on oral health were utilised (N = 630; women, 55.2%; mean age, 49.7 years [SD, 19.2]). Variable selection was guided by the AOHSS. Structural equation modeling was used to analyse relationships amongst the components of the FDI's theoretical model (core elements of oral health, driving determinants, moderating factors, and overall health and well-being).

    Results: The Oral Health Impact Profile (OHIP)-14, xerostomia, and aesthetic satisfaction had statistically significant direct effects on overall health and well-being (p < .05). Driving determinants and moderating factors had statistically significant direct effects on all core elements of oral health (p < .05) except aesthetic satisfaction (p = .616). The predictors explained 24.1% of the variance of the latent variable overall health and well-being. Based on several indices, the proposed model showed acceptable model fit.

    Conclusions: The FDI's theoretical framework can be used to describe different components of oral health and the relationship amongst them in an adult general population. Further research based on the FDI's theoretical framework in other populations and settings is needed to explore complex interactions and possible relationships that form oral health and to investigate other or additional important social determinants.

  • 23.
    Al Zubaidi, Huda
    Jönköping University, School of Health and Welfare, HHJ, Department of Natural Science and Biomedicine.
    Patienter med pacemaker och implanterbar defibrillator inom magnetresonanstomografi: En litteraturstudie om risker och säkerhetsaspekter2023Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    The use of magnetic resonance imaging scans has increased in recent years. This is partly due to the fact that the magnetic resonance imaging is a noninvasive modality, but also because of its high spatial resolution. For many years, magnetic resonance imaging was considered as a contraindicated modality for patients with pacemaker or implantable cardiac defibrillator. The purpose of this thesis was to determine risks associated with performing magnetic resonance imaging in patients with pacemaker or implantable cardiac defibrillator and identifying safety precautions. The study method was conducted as a systematic literature review, which involved structured steps including searching, reviewing, and summarizing scholarly literature. Quality review template was used for the quality assessment of scholarly literature. The result included nine scholarly literatures. Different methods were used in these scholarly literatures to investigate and evaluate the potential risks and safety precautions. The results showed that patients with pacemaker or implantable cardiac defibrillator can undergo magnetic resonance imaging scans with low clinical risk if safety precautions are followed.

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  • 24.
    Alard, Sara
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine.
    Olsson, Isak
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine.
    Utvärdering av Siemens Innovance® Anti-FXa metod på Sysmex CS-2100i för kvantifiering av Rivaroxaban2022Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Rivaroxaban is a direct oral anticoagulant drug (DOAK) used to treat, e.g., deep vein thrombosis. Rivaroxaban inhibits coagulation factor Xa in the coagulation process. More doctors prescribe Rivaroxaban thus, the laboratory at Länssjukhuset Ryhov needs to evaluate the method. Evaluation will enable the laboratory to offer the analysis in routine practice. The purpose of this study was to evaluate anti-FXa assay on Sysmex CS-2100i for the DOAK drug Rivaroxaban. The method evaluation included the evaluation of repeatability and intermediate precision in connection with the analysis of low and high controls. Comparison with validated method analyzed patient plasma and diluted calibrators. Analysis of lowest detection value analyzed plasma from blood donors. The concentration of Rivaroxaban was determined quantitatively by an enzymatic chromogenic method. Repeatability and intermediate precision were approved. Comparison with a validated method for patient samples gave comparable results for the methods, but too few samples were analyzed for reliable values. The calibrators generated high correlation between the theoretical and measured values. Analysis of the lowest detection value gave values between 0-5 ng/ml. The manufacturer’s set limit can therefore be adjusted for Länssjukhuset Ryhov. In conclusion the method is validated at Länssjukhuset Ryhov. 

  • 25.
    Alehagen, Urban
    et al.
    Division of Cardiovascular Medicine, Department of Medicine and Health Sciences, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
    Shamoun, Levar
    Division of Medical Diagnostics, Department of Laboratory Medicine, Jönköping County, Jönköping, Sweden, and Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden .
    Dimberg, Jan
    Jönköping University, School of Health and Welfare, HHJ, Department of Clinical Diagnostics. Jönköping University, School of Health and Welfare, HHJ. Biomedical Platform.
    Wågsäter, Dick
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
    Increased mortality in the A/A genotype of the SNP rs28372698 of interleukin 322021In: Experimental and Therapeutic Medicine, ISSN 1792-0981, E-ISSN 1792-1015, Vol. 21, no 2, article id 127Article in journal (Refereed)
    Abstract [en]

    One of the major causes of mortality in the western hemisphere is cardiovascular disease. Therefore, a variety of markers to identify those at risk are required. Interleukin-32 (IL-32) is a cytokine that is associated with inflammation. The aim of the current study was to investigate variations in single nucleotide polymorphisms (SNPs) of IL-32 and plasma expression, and their associations with mortality. A population of 486 elderly community-living persons were evaluated. The participants were followed for 7.1 years and underwent a clinical examination and blood sampling. SNP analyses of IL-32 rs28372698 using allelic discrimination and plasma measurement of IL-32, using ELISA, were performed. During the follow-up period, 140 (28.8%) all-cause and 87 (17.9%) cardiovascular deaths were registered. No significant difference between mortality and plasma concentration of IL-32 was observed. The A/A genotype group exhibited significantly higher all-cause mortality (P=0.036), and an almost two-fold increased risk in a multivariate Cox regression model for all-cause and cardiovascular mortality. A highly significant difference in all-cause and cardiovascular mortality between the A/A and the T/T groups was demonstrated (P=0.015 resp. P=0.014). In the present study, the cytokine IL-32 was demonstrated to have prognostic information, with an increased risk of all-cause and cardiovascular mortality for those with the A/A genotype rs28372698 of IL-32. The A/A genotype could therefore be regarded as a possible biomarker for mortality risk that may be used to offer optimized cardiovascular patient handling in the future. However, the present study sample was small, and the results should be regarded as hypothesis-generating.

  • 26. Alm, A
    et al.
    Wendt, Lill-Kari
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Oral health.
    Koch, G
    Birkhed, D
    Prevalence of approximal caries in posterior teeth in 15-year-old Swedish teenagers in relation to their caries experience at 3 years of age2007In: Caries Research, ISSN 0008-6568, E-ISSN 1421-976X, Vol. 41, no 5, p. 392-398Article in journal (Refereed)
  • 27. Alm, Anita
    et al.
    Wendt, Lill-Kari
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Oral health.
    Koch, Göran
    Dental treatment in the primary dentition of 7-12 year-old Swedish schoolchildren.2003In: Swedish Dental Journal, ISSN 0347-9994, Vol. 27, no 2, p. 77-82Article in journal (Refereed)
  • 28. Alm, Anita
    et al.
    Wendt, Lill-Kari
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Oral health.
    Koch, Göran
    Dental treatment of the primary dentition in 7-12 year-old Swedish children in relation to caries experience at 6 years of age.2004In: Swedish Dental Journal, ISSN 0347-9994, Vol. 28, no 2, p. 61-66Article in journal (Refereed)
  • 29.
    Alm Mårtensson, Anna
    et al.
    Länsstyrelsen i Jönköping.
    Boström, Anita
    Institutionen för hälsovetenskaper, Karlstads universitet.
    Lindmark, Ulrika
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    Lundgren, Charlie
    Länsstyrelsen Västerbotten.
    Ludvigsson, Mikael
    Linköpings universitet.
    Simmons, Johanna
    Medicinska och geriatriska akutkliniken, Universitetssjukhuset i Linköping.
    Att möta våldsutsatta äldre personer2022In: Äldre personers utsatthet för våld i nära relationer: Interprofessionella perspektiv / [ed] L. Östlund, Lund: Studentlitteratur AB, 2022, p. 183-220Chapter in book (Other academic)
  • 30.
    Alm Mårtensson, Anna
    et al.
    Länsstyrelsen i Jönköping.
    Boström, Anita
    Institutionen för hälsovetenskaper, Karlstads universitet.
    Lindmark, Ulrika
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. Centre for Oral Health. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    Lundgren, Charlie
    Länsstyrelsen Västerbotten.
    Östlund, Lena
    Jönköping University, School of Health and Welfare, HHJ, Institute of Gerontology. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    Ansvarsområden för olika samhällsfunktioner2022In: Äldre personers utsatthet för våld i nära relationer: Interprofessionella perspektiv / [ed] L. Östlund, Lund: Studentlitteratur AB, 2022, p. 91-112Chapter in book (Other academic)
  • 31.
    Altoumaimi, Ahmed
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Isvatten för en bättre bildkvalité vid myokardscintigrafi2015Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Myokardscintigrafi är en nuklearmedicinsk undersökning där hjärtat bedöms utifrån perfusionen i hjärtmuskeln, främst i vänsterkammaren. Detta görs för att diagnosticera patienter med misstanke om kärlkramp eller inför ett kirurgiskt ingrepp såsom ballongdilatation. Ibland kan det uppstå högt tarmupptag som gör att det bli svårt att utvärdera bilderna på hjärtat.

     

    Flera metoder har används tidigare för att minska tarmupptaget såsom dricka mjölk eller äta en stor måltid innan bildtagningen. Syftet med denna randomiserade studie är att se om det kan bli mindre upptag i tarmarna och en bra effekt på bildkvalité om patienten dricker ett glas isvatten precis innan stress bildtagningen.  39 randomiserade patienter ingick totalt i studien som delades i två kvoter, med och utan isvatten. Datainsamling gick ut på att räkna antal pulser på tre ställen på stressbilder med hjälp av ROI. ROI 1 som återspeglade hjärtat jämfördes med ROI 2 samt ROI 3 som är bakgrundsaktivitet för att se hur bakgrundsaktivitet förhåller sig till hjärtat. Resultaten som gjordes genom att jämföra kvot 1 utan isvatten och kvot 2 med isvatten talar om att isvatten hade bättre verkan på ROI2 (lateralt under hjärtat) än ROI3(medialt under hjärtat) där metoden utan isvatten visade sig bättre.

    Download (pdf)
    Isvatten för en bättre bildkvalité vid myokardscintigrafi
  • 32.
    Alvin, Maja
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Department of Natural Science and Biomedicine.
    Lundin, Filippa
    Jönköping University, School of Health and Welfare, HHJ, Department of Natural Science and Biomedicine.
    A comparative study of Tosoh G11 and Bio-Rad D-100 analyzers for HbA1c analysis2023Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Diabetes mellitus is one of the most common diseases worldwide. The continued prevalence increase, together with the complexity of the disease with severe long-term complications makes efficient diagnostical and monitorial methods very important. The determination of glycated hemoglobin, HbA1c, plays an important role in both, underlying the importance of high-quality analytical instruments. Whenever a new instrument is introduced into routine clinical use an evaluation is needed. This study evaluated the agreement between the new Tosoh G11 HbA1c high performance liquid chromatography system as a replacement for the Bio-Rad D-100 at the Chromatographic Department of the Institute of Laboratory Medicine, Faculty of Medicine, University of Debrecen. In total, 66 samples were analyzed using both analyzers and a Bland-Altman comparison was performed together with a correlation study. Additionally, a linearity check, optimal error and routine error testing was carried out specifically for the Tosoh G11. The results showed high agreement between measurements, r=0.9975 (p<0.001) for HbA1c mmol/mol and r=0.9971 (p<0.001) for HbA1c %. High repeatability and accuracy were observed of the Tosoh G11 with the highest variation coefficient of 1.50 % and linearity r =0.9999. The conducted study supports the replacement of the Bio-Rad D-100 to the Tosoh G11.  

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  • 33.
    Anarp, Sofia
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine.
    Lindgren, Elvira
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine.
    Kartläggning av järndepåer hos blodgivare i Region Jönköpings län2022Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    The availability of blood could be crucial for many people; blood donation is, therefore, a vital part of healthcare. Continuous blood donation could affect the blood donors’ iron depots which could lead to an iron deficiency. The aim of the present study was to evaluate and highlight iron depots amongst blood donors in Jönköping County by (i) evaluating the number and proportion of new applicants which did not meet the approved S-ferritin levels for blood donation, (ii) compare the levels of S-ferritin in new registrations and repeated blood donations, (iii) evaluate intake of iron supplements amongst blood donors, (iv) compare the number, proportion and cause for control sampling before and after S-ferritin was introduced as a sampling routine. Data was collected from the Department of Transfusion Medicine, Jönköping, Sweden, and analysed statistically.The result showed that more women than men were not approved for blood donation because of S-ferritin <22 µg/L. By lowering S-ferritin, additional women will be approved for blood donation. Further, the study showed that continuous blood donation leads to decreased iron depots. Groups that were offered iron supplements showed more stable S-ferritin levels over time which implied that all blood donors would benefit from iron supplements, but further studies are required. The majority of the blood donors with S-ferritin ≤100 µg/L were taking their offered iron supplements which showed that the blood donors enabled future blood donations. Lastly, since S-ferritin was introduced as a sampling routine in 2017 the amount of control samplings due to low B-Hb has decreased. This shows that the risk to develop an iron deficiency due to continuous blood donation has decreased in Jönköping County. 

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  • 34.
    Anastassaki, Alkisti
    et al.
    Jönköping University, School of Health Science, HHJ. Oral health.
    Magnusson, Tomas
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Oral health.
    Patients referred to a specialist clinic because of suspected temporomandibular disorders: a survey of 3194 patients in respect of diagnoses, treatments, and treatment outcome.2004In: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 62, no 4, p. 183-192Article in journal (Refereed)
    Abstract [en]

    The aims were to study the patient population at a temporomandibular disorders (TMD) specialist clinic over time, and to try to find variables of importance for treatment outcome. The material consisted of 3194 consecutive patients who were referred to the clinic and underwent a clinical examination during the period 1995-2002. A number of patient and treatment-related variables that had been collected in an electronic database were analyzed retrospectively. The age and sex distribution of the present patient material was in line with several previous investigations of TMD patients. The mean age of both men and women was 42 years, and there was a large preponderance of women. A vast majority of the patients responded positively, and in few visits, on traditional conservative treatment methods. In line with previous studies, no strong predictors for treatment outcome were found. However, the diagnoses of disk displacement without reduction, arthritis in TMJs, and myalgia in masticatory muscles were predictors for a significant improvement, while the diagnosis orofacial pain of unspecified origin predicted a poorer prognosis.

  • 35.
    Anastassaki Köhler, Alkisti
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. Oral health.
    Hugoson, Anders
    Jönköping University, School of Health and Welfare, HHJ. Oral health. Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Magnusson, Tomas
    Jönköping University, School of Health and Welfare, HHJ. Oral health. Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Clinical signs indicative of temporomandibular disorders in adults: time trends and associated factors2013In: Swedish Dental Journal, ISSN 0347-9994, Vol. 37, no 1, p. 1-11Article in journal (Refereed)
    Abstract [en]

    The study aimed to examine possible time trends in the prevalence of clinical signs indicative of temporomandibular disorder (TMD) in an adult population, to analyse possible associations between TMD signs and associated factors and to estimate the need for TMD treatment. Three independent, stratified and randomly selected samples of around 100 individuals in the age groups of 20, 30, 40, 50, 60 and 70 years participated in the Jönköping studies in 1983,1993 and 2003. The study material consisted of 1,693 subjects who, after answering a questionnaire and being interviewed about the presence of TMD symptoms, were clinically examined in terms of the presence of TMD signs according to the Clinical Dysfunction Index (Di) by Helkimo. Associations between clinical signs and the Di as dependent variables and each of the independent variables of age group, gender, reported bruxism, trauma, self-perceived healthiness and the year of investigation were analysed in binary logistic regression models. Estimates of the need for TMD treatment were based on the presence of a combination of severe symptoms and clinical signs. The prevalence of severely impaired jaw movement capacity, relating to horizontal movements, had increased in 2003. The prevalence of muscle pain and temporomandibular joint pain upon posterior palpation was found to vary statistically significantly between 1993 and 2003. Gender differences were noted in these changes overtime. Female gender, advancing age, awareness of bruxism, self-perceived health impairment and the wearing of complete dentures were associated with TMD signs and a higher degree of clinical dysfunction. The estimated need for TMD treatment increased from 5% in 1983 to 8% in 2003 and was higher in women than in men. In conclusion, the results indicate that the prevalence of some TMD signs and of estimated treatment need increased during the period 1983-2003.

  • 36.
    Anastassaki Köhler, Alkisti
    et al.
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Oral health.
    Hugoson, Anders
    Jönköping University, School of Health Science, HHJ. Oral health. Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine.
    Magnusson, Tomas
    Jönköping University, School of Health Science, HHJ. Oral health. Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine.
    Prevalence of symptoms indicative of temporomandibular disorders in adults: cross-sectional epidemiological investigations covering two decades2012In: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 70, no 3, p. 213-223Article in journal (Refereed)
    Abstract [en]

    Objectives. The aims were (1) to study possible secular trends in the prevalence of temporomandibular disorder (TMD) symptoms in adults and (2) to analyse possible associations between TMD symptoms and background factors. Materials and methods. The investigation has a repeated cross-sectional design. Three independent, randomly selected samples of 100 individuals in the age groups of 20, 30, 40, 50, 60 and 70 years, a total of 1704 subjects, participated in the Jönköping studies in 1983, 1993 and 2003. All the subjects were evaluated using a questionnaire and a structured interview relating to the presence of TMD symptoms. Associations between symptoms and the Anamnestic Dysfunction Index (Ai) as dependent variables and each of the independent variables, age group, gender, reported bruxism, trauma (1983), self-perceived health impairment and the year of investigation were analysed in binary logistic regression models. Results. The prevalence of the separate symptoms, apart from for TMJ clicking, did not vary to any statistically significant degree between the different examination years. However, the prevalence of recurrent headache in 20-year-old subjects rose remarkably in 2003 and an increase in the Ai I and Ai II for the whole population was observed during the 20-year period. Reported bruxism, which increased during the study period, and self-perceived health impairment were associated with most of the TMD symptoms and the Ai. Conclusions. An increase in the prevalence of TMD symptoms expressed as Anamnestic Dysfunction Index I and II has been noted over a 20-year period.

  • 37.
    Anastassaki-Köhler, A
    et al.
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Oral health.
    Hugoson, A
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Oral health.
    Magnusson, Tomas
    Jönköping University, School of Health Science, HHJ. Oral health. Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine.
    Clinical signs indicative of temporomandibular disorders in adults: changes over time and associated factors – a preliminary report.2011Conference paper (Refereed)
  • 38.
    Ander, Birgitta
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Behavioural Science and Social Work. Jönköping University, School of Health and Welfare, HHJ. SALVE (Social challenges, Actors, Living conditions, reseach VEnue).
    Bergnéhr, Disa
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Behavioural Science and Social Work. Jönköping University, School of Health and Welfare, HHJ. SALVE (Social challenges, Actors, Living conditions, reseach VEnue).
    Fransson, Eleonor I.
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    Gerdner, Arne
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Behavioural Science and Social Work. Jönköping University, School of Health and Welfare, HHJ. SALVE (Social challenges, Actors, Living conditions, reseach VEnue).
    Where and with whom – contexts of 15-year-olds’ drunkennessManuscript (preprint) (Other academic)
  • 39.
    Ander, Birgitta
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Social Work. Jönköping University, School of Health and Welfare, HHJ. SALVE (Social challenges, Actors, Living conditions, reseach VEnue).
    Fransson, Eleonor I.
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health and Welfare, HHJ. ADULT. Jönköping University, School of Health and Welfare, HHJ. ARN-J (Aging Research Network - Jönköping).
    Bergnéhr, Disa
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Social Work. Jönköping University, School of Health and Welfare, HHJ. SALVE (Social challenges, Actors, Living conditions, reseach VEnue).
    Gerdner, Arne
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Social Work. Jönköping University, School of Health and Welfare, HHJ. SALVE (Social challenges, Actors, Living conditions, reseach VEnue).
    Onset of substance use among early adolescents in Sweden2020In: Journal of Social Work Practice in The Addictions, ISSN 1533-256X, Vol. 20, no 2, p. 105-121Article in journal (Refereed)
    Abstract [en]

    Problem: Early onset, prevalence, and predictors of substance use - tobacco, alcohol-drinking, alcohol-drunkenness, and drugs - were studied in 13 and 14-year-old boys and girls in Sweden.

    Methods: Self-reported data in four communities were used (n = 1,716). A large set of psychological and social factors were tried as predictors of early onset use (n = 1,459).

    Results: There were few gender differences and low prevalence. Primary predictor for early onset in tobacco use was availability; perceived parental approval for alcohol use, and delinquent behaviors for alcohol-drunkenness and drug use.

    Conclusions: Individual behavioral factors and parental norms seem to be most important in this age.

  • 40.
    Andersson, Bengt-Åke
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine.
    Nilsson, Mats
    Department of Health, Medicine and Caring, Linköping University, Linköping, Sweden.
    Oliva, Delmy
    Department of Oncology, Region Jönköping County, Jönköping, Sweden and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
    Impact of single nucleotide polymorphisms and cigarette smoking on cancer risk and survival of patients with head and neck squamous cell carcinoma2022In: Biomarkers, ISSN 1354-750X, E-ISSN 1366-5804, Vol. 27, no 7, p. 694-700Article in journal (Refereed)
    Abstract [en]

    Background: Head and neck squamous cell carcinoma (HNSCC) is a disease involving genetic and lifestyle risk factors such as smoking or high-risk papillomavirus (HR-HPV) infections.

    Objective: This study analyzed 92 single nucleotide polymorphisms (SNPs) associated with smoking and HPV on HNSCC cancer risk and survival among HNSCC patients.

    Material and methods: Eighty-six HNSCC patients (48 non-smoking and 38 smoking) were consecutively included.

    Results: Differences were detected in the analysis of survival and SNP genotypes located in the CXCR2 and COMT. Five SNPs in genes PRKDC, TGFb, XRCC1, Cyp2A6 and CTLA4 were found to be different when comparing SNP genotypes in all patients and all controls as a risk of HNSCC. When comparing SNP genotypes among smoking patients and smoking controls, six SNPs in the genes PFR1, IL10, CCL4, IL6, Ku70, and PRF1 were detected. When comparing SNP genotypes, nine SNPs in CHRNA3, PRKDC, CHARNA5, IFN-γ, ESR1, XRCC1, Cyp2A6, CTLA4, and COMT were different in non-smoking patients and non-smoking controls. No association was found between SNP distribution or patient survival and the impact of HR-HPV.

    Conclusions: The SNPs differed between smokers and non-smokers and could indicate a possible interaction between genetics and smoking. This could play an important role in a better understanding of the pathogenesis of HNSCC.

  • 41.
    Andersson, Emma
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Lindh, Andréa
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Jämförelse mellan konventionell utstryksmetod och vätskebaserad ThinPrepmetod vid preparering av etanolfixerade exsudat2018Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Preparation of effusions for cytological evaluation can be performed with different methods. Conventional smears are performed by spreading the sample directly onto a slide while liquid-based ThinPrep method prepares the sample in an automated process. The aim of this study was to compare conventional smears with liquid-based ThinPrep preparation, with additional acetic acid, of effusions fixated with ethanol. A total of 34 samples of pleural effusions and ascites were included. The samples were prepared with conventional smears and two versions of the ThinPrep method, ThinPrep method 1 and ThinPrep method 2. The preparations were examined by two cytotechnologists based on five criteria; occurrence of cells, occurrence of inflammatory cells, cell morphology, background material and the presence of atypical or malignant cells. The results showed that ThinPrep method 2 obtained equivalent and, in some aspects, even better results compared to conventional smears. In general, the ThinPrep method has several advantages compared to the conventional smears. In particular, it is timesaving when examining the slides, which also benefits the patients. A more comprehensive study is recommended to confirm the results of this study.

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  • 42.
    Andersson, Jelena
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Utvärdering av direktresistensmetod på urinodlingar gentemot EUCAST diskdiffusionsmetod2019Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Urinary tract infections are the second most common reason for prescription of antibiotics in Sweden. Diagnosis of UTIs in urine culture by the standard method requires 18 to 48 hours and an additional 24 hours until antimicrobial testing is available. The direct resistance method provides answers 24 hours earlier than the standard method. The aim of the study was to evaluate the direct resistance method (in-house method) from the microbiological laboratory Unilabs, Skövde on urine cultures from patient samples and compare it with the EUCAST disc diffusion method. For this study, 334 bacterial strains from urinary cultures were used; E. coli (n = 211) E. faecalis (n = 45), Klebsiella spp (n = 37), P. mirabilis (n = 17) and other gram-negative rods (n = 24). The direct resistance method and the EUCAST disk diffusion method were performed in parallel on all bacterial strains and six different types of antibiotics were tested. The diameter of the inhibition zones was measured and categorized according to S, I, R for each antibiotic. From a total of 1674 tested antibiotics 23 discrepancies were found where E. coli represented 13 of these. Mecillinam was the antibiotic where most discrepancies were noted, a total of ten. The agreement between the two methods was 98,6% from 1674 tested antibiotics. The direct resistance method allows a response to the patient 24 hours earlier than the EUCAST disc diffusion method.

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  • 43.
    Andersson Nyberg, Sarah
    et al.
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine.
    Lesjak, Martina
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine.
    Jämförelse mellan ekokardiografiska metoder vid bedömning av vänsterkammarfunktion hos kvinnliga bröstcancerpatienter2015Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Echocardiography is a useful technique which can value the function of the left chamber of the heart by using ejection fraction (EF) and global longitudinal strain (GLS). Today EF is the most common method in assessments of the left chamber function and is calculated by Simpson´s biplanemethod. GLS is a new method that measures the myocardial deformation. It has been proved to be a sensitive method and can detect changes in the myocardium earlier than EF.

     

    The purpose of this study is to compare two echocardiographic methods among 20 female breast cancer patients. Comparisons have been made between EF calculated with Simpson´s biplanemethod (EFbi) and GLS, and between EFbi and EF calculated by GLS (EFGLS). This is a quantitative retrospective study. The data used in this study was collected between October – December 2014 at the Department of Clinical Physiology at the Hospital Ryhov in Jönköping. The method used to analyse the results was McNemar´s test and Kappa value. The results of the study showed that EFbi and GLS gave a modest correspondence between the methods. A reasonable correspondence were observed between EFbi and EFGLS. The conclusion has been drawn from the kappa value.

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  • 44. Andersson, P O
    et al.
    Wikby, Anders
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Hörnquist, J O
    Influence of insulin pen injection frequency on quality of life1990In: Diabetes Care, ISSN 0149-5992, E-ISSN 1935-5548, Vol. 13, no 11, p. 1135-1136Article in journal (Refereed)
  • 45. Andersson, P. O.
    et al.
    Wikby, Anders
    Jönköping University, School of Health Science, HHJ, Dep. of Natural Science and Biomedicine. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Stenström, Ulf
    Jönköping University, School of Health Science, HHJ, Dep. of Behavioural Science and Social Work. Jönköping University, School of Health Science, HHJ. Ageing - living conditions and health.
    Hörnquist, J. O.
    Pen injection and change in metabolic control and quality of life in insulin dependent diabetes mellitus1997In: Diabetes Research and Clinical Practice, ISSN 0168-8227, E-ISSN 1872-8227, Vol. 36, no 3, p. 169-172Article in journal (Refereed)
    Abstract [en]

    A second follow-up of metabolic control and quality of life in insulin dependent diabetes mellitus (IDDM) patients who had switched 3 years before from syringe to multiple pen injection treatment, was carried out. A total of 73 consecutive outpatients were enrolled in the initial follow-up study in 1988, 1 year after their changeover to insulin pen, with their metabolic control and quality of life examined. The present study concerns the reexamination of 65 of them in 1990. Their HbA(1c) level was recorded yearly, already from 1987, on. After an enhancement of metabolic control in 1988, exhibited primarily by patients with fewer syringe injections before pen treatment, control up to 1990 was found to have regressed to about baseline level or to have gradually declined. Patients who perceived their ability to self-test blood glucose to have decreased exhibited the least satisfactory course of metabolic control. This is seen to indicate that maintaining self-testing in multiple injection insulin treatment is a very real challenge to this regimen.

  • 46.
    Andersson, Wilma
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Department of Natural Science and Biomedicine.
    Grönlund, Julia
    Jönköping University, School of Health and Welfare, HHJ, Department of Natural Science and Biomedicine.
    Utvärdering av INNOVANCE D-Dimer reagens2023Independent thesis Basic level (university diploma), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    D-Dimer is a fibrinogen degradation product which indicates thrombotic diseases, amongst other conditions, when reported in high levels. It is more frequently used as an exclusion test when suspecting thrombotic diseases due to the occurrence of high levels of D-Dimer in various conditions. The unit which is currently used for D-Dimer analysis at Clinical chemistry, Ryhov Jönköping is D-Dimer Units. In attempt to standardize the method used for analysis of D-Dimer, the INNOVANCE® D-Dimer reagent was evaluated. INNOVANCE® D-Dimer reagent is reported in the unit Fibrinogen Equivalent Units. Analysis of D-Dimer causes problems due to its heterogeneity and the many existing methods of analysis. The many ways of reporting results in different units are also creating confusion. The purpose of this study was to evaluate INNOVANCE® D-Dimer reagent at Clinical chemistry, Ryhov to introduce usage of Fibrinogen Equivalent Units. The method evaluation included repeatability test and intermediate precision using the INNOVANCE® Controls and analyzing patient samples. The results of the patient samples were compared to the results obtained from the same samples at Lunds University hospital and Sahlgrenska University hospital. There was a clear correlation between all instruments and institutions. In conclusion, INNOVANCE® D-Dimer was approved for introduction at Clinical chemistry, Ryhov.

  • 47.
    Andraus David, Muna
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Department of Natural Science and Biomedicine.
    David, Maria
    Jönköping University, School of Health and Welfare, HHJ, Department of Natural Science and Biomedicine.
    Åldersrelaterade Skillnader I Lumendiameter Och Flödeshastighet I CCA Och ICA: En jämförelse av åldersgrupper2023Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Summery

    Age-related differences in lumen diameter and blood flow velocity in CCA and ICA: A comparison of age groups

    Carotid duplex is used to diagnose diseases of the carotid vessels and assess the degree of atherosclerosis. The study investigated whether there was a significant difference in lumen diameter (LD) and flow velocity in the dexter carotid artery (CCA dx) and dexter internal carotid artery (ICA dx) between two age groups (Group A: 18–25 years old, Group B: 48– 55 years old). A total of 30 people participated in each group. A significant difference in LD was identified for CCA dx (p=0.014) but not for ICA dx (p=0.161). LD in CCA dx in group B was greater than LD in group A. A significant difference in peak systolic velocity (PSV) between group A and group B was identified for CCA dx (p <0.001) and ICA dx (p <0.001). Flow velocity in both CCA dx and ICA dx was lower in group B compared to group A. No significant difference in end-diastolic velocity (EDV) for CCA dx (p=0.306) and ICA dx (p=0.05) was identified. A correlation between BMI and LD in CCA dx and ICA dx was examined within the groups. No significant correlations were identified for CCA dx (ρ=0.352) and ICA dx (ρ=0.114) in group A. A significant correlation was identified for CCA dx in group B (ρ =0.423*), but not for ICA dx (ρ =0.253).

    Keywords: Carotis duplex, vascular physiology, peak systolic velocity, end-diastolic velocity, BMI

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  • 48.
    André, Ida
    Jönköping University, School of Health and Welfare, HHJ, Dept. of Natural Science and Biomedicine.
    En sonografisk jämförelse mellan blodflödeshastigheter i arteria carotis interna och arteria carotis externa2022Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Ultrasound examination of the internal carotid artery (ICA) and the external carotid artery (ECA) is performed in physiological clinics to assess the blood flow velocity in the vessels. Furthermore, it can be used in the diagnosis of plaque and stenoses. Treatment of stenosis is important as it can lead to stroke and transient ischemic attack (TIA). The purpose of this study is to compare the maximum blood flow velocity in ECA and ICA and allocate a possible difference between the right and left side. The study included 36 participants between the ages of 20–27. The result was analyzed using a paired t-test and a correlation analysis. A statistical significance was identified when comparing ICA and ECA on the same side. No significant difference was found when comparing left and right ECA and ICA. One correlation was detected between left and right ECA and between left and right ICA. Another correlation was identified between ECA bilaterally and ICA dexter. The conclusion of this study is that there is a significant difference between the flow velocity in ICA and ECA and therefore it is not possible to use the same reference values ​​for both vessels.

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  • 49.
    André, Ida
    et al.
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Suez, Issis
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Patientupplevelser av informationsbehovet i samband med en magnetresonanstomografisk-mammografi: En intervjustudie2015Independent thesis Basic level (degree of Bachelor), 5 credits / 7,5 HE creditsStudent thesis
    Abstract [sv]

    Magnetresonanstomografiska undersökningar av brösten (MRT-mammografi) har utförts i över två decennier. Undersökningen görs vid mammografiskt oklara fynd, planering inför kirurgi samt vid kontroll när det finns ökad risk för bröstcancer. Informationen inför en magnetresonanstomografisk undersökning är avgörande då information angående undersökningsprocedurer ökar patientmedverkandet vilket kan gynna bildkvalitén inför diagnostik. Syftet med studien var att undersöka patientupplevelser av informationsbehovet i samband med en MRT-mammografisk undersökning. Urvalet för studien bestod av 6 patienter som genomgick en MRT-mammografi under månaderna februari till april 2015. Studien har en kvalitativ ansats där enskilda telefonintervjuer gjorts. Insamlad data har analyserats med innehållsanalys som resulterat i 4 kategorier: Informationsmetod, Kunskap och tidigare erfarenheter, Röntgensjuksköterskans interaktion med patienter och önskat informationsinnehåll. Informationen i samband med undersökningen anses vara tillräcklig och bra enligt de flesta informanterna. Brister belyses dock i den nuvarande informationen och förbättringsutrymmen så som information på andra språk, vägbeskrivning samt information om undersökningsproceduren har angivits. En viktig kategori som synliggjorts under studiens gång är Röntgensjuksköterskans interaktion med patienter. Röntgensjuksköterskans information är ett komplement till informationen som givits i samband med en MRT-mammografi och har en betydande roll i mötet med patienter. 

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  • 50.
    André Kramer, Ann-Catrin
    Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
    Kariesutveckling i primära bettet hos barn från tre till sex års ålder2011Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
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