This paper explores the determinants of productivity in the countries of Eastern Europe (EE) through the perspective of 'narrow' and 'broad' national systems of innovation (NSI). Based on panel econometrics, it examines the extent to which systems in EE could be considered '(in)efficient'. Our results suggest that the EE countries have lower levels of productivity than might be expected given their research and development (R&D), innovation and production capabilities. The inefficiencies of 'broad' NSI are compounded by the inefficiencies of 'narrow' NSI in terms of generating numbers of science and technology publications and resident patents relative to R&D employment compared to the rest of the world. Our results point to an important distinction between technology and production capability as the drivers of productivity improvements and provide some policy implications.