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Treatment of peri-implantitis: Clinical outcome of chloramine as an adjunctive to non-surgical therapy: a randomized clinical trial
Department of Periodontology, Public Dental Health Service, Kristianstad.
Department of Cariology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Gothenburg.
Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine. (Adult)ORCID iD: 0000-0001-5145-8220
2017 (English)In: Clinical Oral Implants Research, ISSN 0905-7161, E-ISSN 1600-0501, Vol. 28, no 1, 43-48 p.Article in journal (Refereed) Published
Abstract [en]

Purpose: To evaluate the adjunctive clinical effects of a chloramine to non-surgical treatment of peri-implantitis.

Material and methods: Eighteen individuals diagnosed with peri-implantitis (clinical signs of inflammation and progressive bone loss) on at least two implants were included. Clinical variables; plaque accumulation (Pl), probing depth (PD), clinical attachment level (CAL) and bleeding on probing (BoP), were recorded at baseline and at 3-month follow-up. Primary clinical efficacy variable was the change in the number of sites with BoP. The implants were randomized into two different treatment groups: test and control. Both implants received supra- and submucosal debridement by ultrasonic instrumentation supplemented with hand instruments. The implants assigned to the test group first received local applications of a chloramine gel (PerisolvTM; RLS Global AB, Gothenburg, Sweden) followed by mechanical instrumentation. The oral hygiene was checked at 6 weeks.

Results: After 3 months, implants of both groups showed statistically significant reduction (P < 0.001) in the number of BoP-positive sites compared with baseline. The reduction of BoP-positive sites in the test group changed from 0.97 (SD 0.12) to 0.38 (SD 0.46), and in the control group from 0.97 (SD 0.12) to 0.31 (SD 0.42). Between-group comparisons revealed no statistically significant differences at baseline and after 3 months, for BoP or any of the other variables.

Conclusion: In the present randomized clinical trial of peri-implantitis therapy; non-surgical mechanical debridement with adjunctive use of a chloramine is equally effective in the reduction of mucosal inflammation as conventional non-surgical mechanical debridement up to 3 months.

Place, publisher, year, edition, pages
John Wiley & Sons, 2017. Vol. 28, no 1, 43-48 p.
Keyword [en]
chloramine, non-surgical therapy, peri-implantitis, surface decontamination
National Category
Dentistry
Identifiers
URN: urn:nbn:se:hj:diva-28904DOI: 10.1111/clr.12612ISI: 000394181300007PubMedID: 26013241Scopus ID: 2-s2.0-84930259856OAI: oai:DiVA.org:hj-28904DiVA: diva2:891949
Available from: 2016-01-08 Created: 2016-01-08 Last updated: 2017-03-27Bibliographically approved

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