Cyber-Physical Systems (CPS) can provide for significant benefits in different areas of human activities. However, the existing gap between methods, modelling approaches and viewpoints of the disciplines involved into CPS development creates significant difficulties for creating viable CPS solutions. In this paper we are trying to bridge this gap via linking business model and system design and configuration disciplines. It is investigated how a business model captured in an enterprise model can be used for configuring a CPS which is part of implementing the business model. The results are illustrated on an example from the transportation industry.