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The influence of age, gender, insulin dose, BMI, and blood pressure on metabolic control in young patients with type 1 diabetes
Jönköping University, School of Health and Welfare, The Jönköping Academy for Improvement of Health and Welfare. Ryhov City Hospital, Jönköping.
Linköping University Hospital.
Linköping University Hospital.
2015 (English)In: Pediatric Diabetes, ISSN 1399-543X, E-ISSN 1399-5448, Vol. 16, no 8, 581-586 p.Article in journal (Refereed) Published
Abstract [en]

Objective

To explore the relationship between certain clinical variables and metabolic HbA1c at diagnosis correlated to HbA1c at follow-up (p < 0.001). There was a clear gender difference regarding HbA1c. Girls had higher values both at diagnosis and at follow-up (p < 0.001). Girls also had lower BMI and pH at diagnosis than boys (p < 0.001). In contrast, girls with the highest body mass index (BMI) at follow-up had higher mean HbA1c at follow-up in 2010 (p < 0.001). Having a mother and/or a father with high BMI implied higher HbA1c at diagnosis (p < 0.003).

Conclusions

HbA1c at diagnosis seems to predict metabolic control years later. There is a gender difference at diagnosis as female patients have higher HbA1c than males at diagnosis as well as at follow up. As metabolic control is very much correlated to complications there is a need to early identify patients at risk of poor metabolic control. Even though we do not know whether a high HbA1c level is mainly due to severity of the disease or to behavioral patterns, new ways to treat and support these children, especially girls, are needed.

Place, publisher, year, edition, pages
2015. Vol. 16, no 8, 581-586 p.
Keyword [en]
children, gender, HbA1c, metabolic control, quality register, type 1 diabetes
National Category
Pediatrics Endocrinology and Diabetes
Identifiers
URN: urn:nbn:se:hj:diva-28447DOI: 10.1111/pedi.12219ISI: 000363929400003PubMedID: 25270077Scopus ID: 2-s2.0-84946484101OAI: oai:DiVA.org:hj-28447DiVA: diva2:876639
Available from: 2015-12-04 Created: 2015-12-02 Last updated: 2015-12-04Bibliographically approved

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CiteExportLink to record
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