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Patient-reported outcomes as predictors of 10-year survival in women after acute myocardial infarction
Jönköping University, School of Health and Welfare, HHJ, Dep. of Nursing Science. Jönköping University, School of Health and Welfare, HHJ. Quality improvements, innovations and leadership in health care and social work.
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2010 (English)In: Health and Quality of Life Outcomes, E-ISSN 1477-7525, Vol. 8, article id 140Article in journal (Refereed) Published
Abstract [en]

Background: Patient-reported outcomes are increasingly seen as complementary to biomedical measures. However, their prognostic importance has yet to be established, particularly in female long-term myocardial infarction (MI) survivors. We aimed to determine whether 10-year survival in older women after MI relates to patient-reported outcomes, and to compare their survival with that of the general female population.

Methods: We included all women aged 60-80 years suffering MI during 1992-1997, and treated at one university hospital in Norway. In 1998, 145 (60% of those alive) completed a questionnaire package including socio-demographics, the Sense of Coherence Scale (SOC-29), the World Health Organization Quality of Life Instrument Abbreviated (WHOQOL-BREF) and an item on positive effects of illness. Clinical information was based on self-reports and hospital medical records data. We obtained complete data on vital status.

Results: The all-cause mortality rate during the 1998-2008 follow-up of all patients was 41%. In adjusted analysis, the conventional predictors s-creatinine (HR 1.26 per 10% increase) and left ventricular ejection fraction below 30% (HR 27.38), as well as patient-reported outcomes like living alone (HR 6.24), dissatisfaction with self-rated health (HR 6.26), impaired psychological quality of life (HR 0.60 per 10 points difference), and experience of positive effects of illness (HR 6.30), predicted all-cause death. Major adverse cardiac and cerebral events were also significantly associated with both conventional predictors and patient-reported outcomes. Sense of coherence did not predict adverse events. Finally, 10-year survival was not significantly different from that of the general female population.

Conclusion: Patient-reported outcomes have long-term prognostic importance, and should be taken into account when planning aftercare of low-risk older female MI patients.

Place, publisher, year, edition, pages
BioMed Central, 2010. Vol. 8, article id 140
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Nursing
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URN: urn:nbn:se:hj:diva-14164DOI: 10.1186/1477-7525-8-140ISI: 000287592900002PubMedID: 21108810Scopus ID: 2-s2.0-78649334178OAI: oai:DiVA.org:hj-14164DiVA, id: diva2:382054
Available from: 2010-12-29 Created: 2010-12-29 Last updated: 2024-07-04Bibliographically approved

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