Healthcare is often delivered by teams made up of culturally and demographically diverse members. Group diversity, for example, in terms of age, gender and/or culture, can bring a range of benefits, but also complex challenges for the functioning of healthcare teams. The literature suggests that cultural diversity is the most difficult issue for these teams to manage. Therefore, the aim of this study is to explore the perceived needs of healthcare professionals when working in culturally diverse teams. Data were collected through individual interviews with 23 healthcare professionals working in two hospitals in one municipality in southern Sweden. The data were analysed using an inductive content analysis approach. In the process of the analysis, two main categories of needs emerged: Favourable working conditions and guidance, and Commonalities. The findings highlight the need for the right work and team climate, as well as leadership, for culturally diverse teams to function well. In addition, the implementation and communication of rules and regulations, clarity of roles, and a shared understanding of cultural diversity, language, and the culture of care are important for these teams. By uncovering the needs expressed by healthcare professionals in relation to working in culturally diverse teams, our research provides important insights into the key enablers of the benefits of team diversity in the healthcare context.