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Image quality and myocardial scar size determined with magnetic resonance imaging in patients with permanent atrial fibrillation: A comparison of two imaging protocols
Department of Clinical Physiology, Ryhov County Hospital, Jönköping, Sweden; Center for Medical Image Science and Visualization, Linköping University, Linköping, Sweden.
Department of Radiology, Ryhov County Hospital, Jönköping, Sweden.
Department of Clinical Physiology, Ryhov County Hospital, Jönköping, Sweden.
Department of Clinical Physiology, Ryhov County Hospital, Jönköping, Sweden.
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2010 (English)In: Clinical Physiology and Functional Imaging, ISSN 1475-0961, E-ISSN 1475-097X, Vol. 30, no 2, p. 122-129Article in journal (Refereed) Published
Abstract [en]

Background: Magnetic resonance imaging (MRI) of the heart generally requires breath holding and a regular rhythm. Single shot 2D steady-state free precession (SS_SSFP) is a fast sequence insensitive to arrhythmia as well as breath holding. Our purpose was to determine image quality, signal-to-noise (SNR) and contrast-to-noise (CNR) ratios and infarct size with a fast single shot and a standard segmented MRI sequence in patients with permanent atrial fibrillation and chronic myocardial infarction.

Methods: Twenty patients with chronic myocardial infarction and ongoing atrial fibrillation were examined with inversion recovery SS_SSFP and segmented inversion recovery 2D fast gradient echo (IR_FGRE). Image quality was assessed in four categories: delineation of infarcted and non-infarcted myocardium, occurrence of artefacts and overall image quality. SNR and CNR were calculated. Myocardial volume (ml) and infarct size, expressed as volume (ml) and extent (%), were calculated, and the methodological error was assessed.

Results: SS_SSFP had significantly better quality scores in all categories (P = 0·037, P = 0·014, P = 0·021, P = 0·03). SNRinfarct and SNRblood were significantly better for IR_FGRE than for SS_SSFP (P = 0·048, P = 0·018). No significant difference was found in SNRmyocardium and CNR. The myocardial volume was significantly larger with SS_SSFP (170·7 versus 159·2 ml, P<0·001), but no significant difference was found in infarct volume and infarct extent.

Conclusion: SS_SSFP displayed significantly better image quality than IR_FGRE. The infarct size and the error in its determination were equal for both sequences, and the examination time was shorter with SS_SSFP.

Place, publisher, year, edition, pages
John Wiley & Sons, 2010. Vol. 30, no 2, p. 122-129
Keywords [en]
Atrial fibrillation, Magnetic resonance imaging, Myocardial infarction, Segmented inversion recovery 2D fast gradient echo, Single shot inversion recovery 2D steady-state free precession, anticoagulant agent, antihypertensive agent, beta adrenergic receptor blocking agent, hydroxymethylglutaryl coenzyme A reductase inhibitor, oral antidiabetic agent, adult, aged, article, artifact, chronic disease, clinical article, clinical protocol, contrast enhancement, controlled study, disease severity, female, heart atrium fibrillation, heart infarction size, human, image display, image quality, intermethod comparison, male, nuclear magnetic resonance imaging, priority journal, signal noise ratio, steady state, Aged, 80 and over, Artifacts, Cicatrix, Electrocardiography, Humans, Middle Aged, Myocardium, Reproducibility of Results, Systole, Ventricular Function, Left
National Category
Cardiology and Cardiovascular Disease Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:hj:diva-63326DOI: 10.1111/j.1475-097X.2009.00914.xISI: 000274438800006PubMedID: 20041907Scopus ID: 2-s2.0-76949107327OAI: oai:DiVA.org:hj-63326DiVA, id: diva2:1827095
Available from: 2024-01-12 Created: 2024-01-12 Last updated: 2025-02-10Bibliographically approved

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