The determinants of occupational accidents from a social, cultural and a working condi-tions combined perspective are unveiled considering the level of analysis of the European nation. Fatal and non-fatal work accidents in 2014, collected and provided by Eurostat, are correlated with country by country results of the 7th European Social Survey (ESS) (2014 data). This informs on social deter-minants of work accidents. National Dimensions of Culture proposed by Gert Hofstede are correlated with country by country results of the ESS informing on cultural determinants of the European Social Dimensions reported on the ESS. Moreover, considering data from the 6th European Working Condi-tions Survey (2015 data), working conditions, on a country by country basis as well, are further consid-ered and analyzed from the perspective of fatal and nonfatal accidents and from the perspective of social and cultural dimensions. This multiple pronged study of association unveils interesting associa-tions between fatal and non-fatal work accidents and working conditions, as well as between fatal and non-fatal work accidents and social and cultural dimensions, and, between social and cultural dimen-sions and working conditions, taking the European country as a unit of analysis. The findings shed light on the interconnectedness of the distinct domains under study, as well as informing policy development towards creating tailor made approaches suiting each country reality within the countries encompassed in the analysis.