Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies - An Update
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Center for Economic and Social Research, University of Southern California, Los Angeles, CA, United States.
Center for Economic and Social Research, University of Southern California, Los Angeles, CA, United States.
Department of Psychology, Indiana University Southeast, New Albany, IN, United States.ORCID iD: 0000-0003-2346-2470
Show others and affiliations
2019 (English)In: Twin Research and Human Genetics, ISSN 1832-4274, E-ISSN 1839-2628, Vol. 22, no 6, p. 809-816Article in journal (Refereed) Published
Abstract [en]

The Interplay of Genes and Environment across Multiple Studies (IGEMS) is a consortium of 18 twin studies from 5 different countries (Sweden, Denmark, Finland, United States, and Australia) established to explore the nature of gene-environment (GE) interplay in functioning across the adult lifespan. Fifteen of the studies are longitudinal, with follow-up as long as 59 years after baseline. The combined data from over 76,000 participants aged 14-103 at intake (including over 10,000 monozygotic and over 17,000 dizygotic twin pairs) support two primary research emphases: (1) investigation of models of GE interplay of early life adversity, and social factors at micro and macro environmental levels and with diverse outcomes, including mortality, physical functioning and psychological functioning; and (2) improved understanding of risk and protective factors for dementia by incorporating unmeasured and measured genetic factors with a wide range of exposures measured in young adulthood, midlife and later life.

Place, publisher, year, edition, pages
Cambridge University Press, 2019. Vol. 22, no 6, p. 809-816
Keywords [en]
Dementia, early life adversity, gene–environment interplay, health, socioeconomic status
National Category
Public Health, Global Health, Social Medicine and Epidemiology Medical Genetics and Genomics
Identifiers
URN: urn:nbn:se:hj:diva-46509DOI: 10.1017/thg.2019.76ISI: 000517442200061PubMedID: 31544729Scopus ID: 2-s2.0-85072661257Local ID: HOA HHJ 2019;HHJARNISOAI: oai:DiVA.org:hj-46509DiVA, id: diva2:1359565
Available from: 2019-10-09 Created: 2019-10-09 Last updated: 2025-02-10Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMedScopus

Authority records

Finkel, DeborahDahl Aslan, Anna K.

Search in DiVA

By author/editor
Finkel, DeborahDahl Aslan, Anna K.
By organisation
HHJ, Institute of GerontologyHHJ. ARN-J (Aging Research Network - Jönköping)
In the same journal
Twin Research and Human Genetics
Public Health, Global Health, Social Medicine and EpidemiologyMedical Genetics and Genomics

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 159 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf