Introduction: Self-stigma occurs when individuals internalise negative societal perceptions of their health condition; it is common in psychosis. Self-stigma may affect engagement and performance in occupational therapy prioritized domains such as work and independently living, as individuals internalise beliefs these are not within the limited capabilities of a person with their condition. The aim of this study was to explore the relationship between self-stigma and occupation in adults with psychotic illnesses.

Method: A systematic review was undertaken across multiple databases utilizing the keywords and synonyms of ‘occupation’, ‘psychosis’, ‘self-stigma’. Literature was appraised for quality using relevant Strengthening the Reporting of Observational Studies in Epidemiology or Critical Appraisal Skills Program checklists, assigned relevant Oxford Centre for Evidence Based Medicine levels, and analysed using theoretically-driven thematic analysis, and a transactionalist frame of reference.

Findings: Of 336 articles found, 16 met inclusion criteria and were reviewed. The results indicated that levels of self-stigma were inversely related to outcomes across all of the occupational domains: productivity, leisure, and self-care.

Conclusion: Occupational therapists must be aware of the role of self-stigma as a factor that impedes occupational function in people with psychotic illness. Intervention should include strategies to increase resilience and decrease negative self-perceptions.