Business models play an important role in establishing sustainable intermediary platforms for e-health services in two-sided markets. In this chapter, we describe different types of business models and potential revenue and reimbursement schemes based on the Swedish HealthForMe platform. In doing so, we also discuss many of today's open questions and challenges to be addressed by intermediaries operating in two-sided e-health markets. We conclude this chapter by providing an overview of key implications and success factors for owners of such intermediary platforms, and offer an outlook to focal research areas within the context of business models for two-sided markets.