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Hur kroppens position påverkar antalet avbrott i den isobariska konturen under högupplöst esophagusmanometri
Jönköping University, School of Health and Welfare, HHJ. Biomedical Platform.
2017 (Swedish)Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
Sustainable development
Sustainable Development
Alternative title
How the body position affect the frequency of disruptions in the isobaric contour during high-resolutions esophagus manometry (English)
Abstract [sv]

Nedsatt motilitet i esophagus kan vara en orsak till dysphagi. Högupplöst esophagusmanometri (HRM) är "golden standard" för att utvärdera esophagus motilitet. Defekter av motiliteten kan ses som avbrott i den isobariska konturen (IBC). Det finns ett samband mellan avbrott och inkomplett bolus clearance. Referensvärdena för HRM är utformade för att patienten ska ligga ner och svälja under undersökningen. Kroppens läge påverkar esophagus och värdena för HRM ändras signifikant beroende på om patienten ligger ned eller sitter upp. Det pågår diskussioner kring om undersökningen borde innefatta sväljningar i både liggande och sittande position för att öka den diagnostiska säkerheten. Denna studie innefattade 12 stycken patienter som frivilligt genomgick 10 extra sväljningar sittande utöver de i liggande position. En jämförelse i antalet avbrott i IBC gjordes mellan sväljningarna sittandes och liggandes. Resultatet visade att 24 av 118 sväljningar liggande hade avbrott i IBC och 94 var utan avbrott. När patienterna satt upp hade 68 av 120 sväljningar avbrott i IBC och 52 sväljningar utan avbrott. Hypotesen bekräftades då det föreligger en signifikant skillnad i antalet avbrott mellan sittande och liggande position. Det förekom fler avbrott i sittande position och avbrotten blev också längre i sittande position. Fortsatta studier med större urval erfordras.

Abstract [en]

Reduced motility in the esophagus can be a cause of dysphagia. High-resolution esophagus manometry (HRM) is the golden standard for evaluating esophageal motility. Defects of the motility can be seen as disruptions in the isobaric contour (IBC). There is a correlation between disruptions and incomplete bolus clearance. The references for HRM are made for the patient to lie down and swallow for the examination. The position of the body affects the esophagus and the values for HRM changes significantly depending on whether the patients is lying down or sitting up. There are discussions about whether the procedure should include both supine and sitting position to increase diagnostic reliability. This study included 12 patients who voluntarily underwent 10 additional swallows sitting up in addition to the supine position. A comparison of the disruptions in IBC was made between the swallows sitting and supine. The results showed that 24 out of 118 supine swallows had disruptions in IBC and 94 were without. When the patients sat up, 68 out of 120 swallows had disruptions in IBC and 52 were without. The hypothesis was confirmed as there were more disruptions in the sitting position and the disruptions were longer. Further studies are required.

Place, publisher, year, edition, pages
2017. , 21 p.
Keyword [sv]
dysphagi, ineffektiv esophagusmotilit, Clouse plot, topografisk färgkontur, hypotensiv peristaltik, inkomplett bolus clearance
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:hj:diva-36064ISRN: JU-HHJ-BLA-1-20170038OAI: oai:DiVA.org:hj-36064DiVA: diva2:1109209
Subject / course
HHJ, Biomedical Laboratory Science
Supervisors
Examiners
Available from: 2017-06-19 Created: 2017-06-13 Last updated: 2017-06-19Bibliographically approved

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