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Prevalence of cervical infection and genotype distribution of human Papilloma virus among females in Da Nang, Vietnam
Department of Medical Laboratory, Da Nang University of Medical Technology and Pharmacy, Da Nang, Vietnam.
Department of Medical Laboratory, Da Nang University of Medical Technology and Pharmacy, Da Nang, Vietnam.
Jönköping University, School of Health and Welfare, HHJ, Dep. of Natural Science and Biomedicine.
Karolinska University Laboratory, Karolinska University Hospital, Stockholm, Sweden.
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2017 (English)In: Anticancer Research, ISSN 0250-7005, E-ISSN 1791-7530, Vol. 37, no 3, 1243-1247 p.Article in journal (Refereed) Published
Abstract [en]

Aim: The goal of the present study was to determine the prevalence and distribution of high-risk human papilloma virus (HPV) genotypes in women from two districts in and around Da Nang city, Vietnam.

Materials and Methods: All participants were randomly selected, 200 from the Hai Chau district and 200 from the Son Tra district. The detection and genotyping of HPV were performed by real-time polymerase chain reaction (PCR) technique.

Results: Out of a total of 400 women, we found that 38 (9.5%) were infected with a high-risk HPV genotype, the most prevalent genotypes being 16, 18, 58 and 59. By assessment of the HPV findings in relation to sociodemographic characteristics, we found significant differences between the two study districts and between the age groups, as well as differences associated with occupation and the use of contraceptives.

Conclusion: The proportion of high–risk genotypes other than 16 and 18 was relatively high, and since the HPV genotype distribution is known to vary greatly across populations, the information from this study can be used for planning of screening and vaccination programs in Da Nang.

Place, publisher, year, edition, pages
International Institute of Anticancer Research , 2017. Vol. 37, no 3, 1243-1247 p.
Keyword [en]
Cervical cancer; human papilloma virus; high-risk HPV genotype; prevalence; Vietnam
National Category
Cancer and Oncology
Identifiers
URN: urn:nbn:se:hj:diva-35221OAI: oai:DiVA.org:hj-35221DiVA: diva2:1083218
Available from: 2017-03-20 Created: 2017-03-20 Last updated: 2017-03-20Bibliographically approved

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