Job strain and cardiovascular disease risk factors: Meta-analysis of individual-participant data from 47,000 men and womenSchool of Public Health, Université libre de Bruxelles, Brussels, Belgium.
Department of Public Health, Ghent University, Ghent, Belgium.
Department of Public Health, Ghent University, Ghent, Belgium.
Institute for Medical Sociology, Medical Faculty, University of Düsseldorf, Düsseldorf, Germany.
Department of Cardiology, West-German Heart Center Essen, University Duisburg-Essen, Essen, Germany.
School of Community and Social Medicine, University of Bristol, Bristol, United Kingdom.
Department of Epidemiology and Public Health, University College London, London, United Kingdom.
Institute for Medical Informatics, Biometry, and Epidemiology, Faculty of Medicine, University Duisburg-Essen, Essen, Germany.
School of Public Health, Université libre de Bruxelles, Brussels, Belgium.
Department of Health Sciences, Mid Sweden University, Sundsvall, Sweden.
German Research Center for Environmental Health, Neuherberg, Germany.
Institute for Medical Sociology, Medical Faculty, University of Düsseldorf, Düsseldorf, Germany.
Department of Epidemiology and Public Health, University College London, London, United Kingdom.
Department of Psychology, Umeå University, Umeå, Sweden.
National Research Centre for the Working Environment, Copenhagen, Denmark.
Institute for Medical Sociology, Medical Faculty, University of Düsseldorf, Düsseldorf, Germany.
Department of Epidemiology and Public Health, University College London, London, United Kingdom.
Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden.
Stress Research Institute, Stockholm University, Stockholm, Sweden.
Stress Research Institute, Stockholm University, Stockholm, Sweden.
Department of Epidemiology and Public Health, University College London, London, United Kingdom.
Department of Epidemiology and Public Health, University College London, London, United Kingdom.
Department of Epidemiology and Public Health, University College London, London, United Kingdom.
Finnish Institute of Occupational Health, Helsinki and Tampere, Finland.
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2013 (English)In: PLOS ONE, E-ISSN 1932-6203, Vol. 8, no 6, p. e67323-Article in journal (Refereed) Published
Abstract [en]
Background
Job strain is associated with an increased coronary heart disease risk, but few large-scale studies have examined the relationship of this psychosocial characteristic with the biological risk factors that potentially mediate the job strain – heart disease association.
Methodology and Principal Findings
We pooled cross-sectional, individual-level data from eight studies comprising 47,045 participants to investigate the association between job strain and the following cardiovascular disease risk factors: diabetes, blood pressure, pulse pressure, lipid fractions, smoking, alcohol consumption, physical inactivity, obesity, and overall cardiovascular disease risk as indexed by the Framingham Risk Score. In age-, sex-, and socioeconomic status-adjusted analyses, compared to those without job strain, people with job strain were more likely to have diabetes (odds ratio 1.29; 95% CI: 1.11–1.51), to smoke (1.14; 1.08–1.20), to be physically inactive (1.34; 1.26–1.41), and to be obese (1.12; 1.04–1.20). The association between job strain and elevated Framingham risk score (1.13; 1.03–1.25) was attributable to the higher prevalence of diabetes, smoking and physical inactivity among those reporting job strain.
Conclusions
In this meta-analysis of work-related stress and cardiovascular disease risk factors, job strain was linked to adverse lifestyle and diabetes. No association was observed between job strain, clinic blood pressure or blood lipids.
Place, publisher, year, edition, pages
2013. Vol. 8, no 6, p. e67323-
National Category
Public Health, Global Health, Social Medicine and Epidemiology Occupational Health and Environmental Health
Identifiers
URN: urn:nbn:se:hj:diva-21569DOI: 10.1371/journal.pone.0067323ISI: 000322342800129PubMedID: 23840664Scopus ID: 2-s2.0-84879259859Local ID: HHJADULTISOAI: oai:DiVA.org:hj-21569DiVA, id: diva2:631867
2013-06-242013-06-242021-06-14Bibliographically approved