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Body mass index across midlife and cognitive change in late life
Högskolan i Jönköping, Hälsohögskolan, HHJ, Institutet för gerontologi. Högskolan i Jönköping, Hälsohögskolan, HHJ. Åldrande - livsvillkor och hälsa.
Högskolan i Jönköping, Hälsohögskolan, HHJ. Åldrande - livsvillkor och hälsa. Högskolan i Jönköping, Hälsohögskolan, HHJ, Avd. för naturvetenskap och biomedicin.ORCID-id: 0000-0001-9042-4832
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2013 (Engelska)Ingår i: International Journal of Obesity, ISSN 0307-0565, E-ISSN 1476-5497, Vol. 37, nr 2, s. 296-302Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background: High midlife body mass index (BMI) has been linked to a greater risk of dementia in late life, but few have studied the effect of BMI across midlife on cognitive abilities and cognitive change in a dementia-free sample.

Methods: We investigated the association between BMI, measured twice across midlife (mean age 40 and 61 years, respectively), and cognitive change in four domains across two decades in the Swedish Adoption/Twin Study of Aging.

Results: Latent growth curve models fitted to data from 657 non-demented participants showed that persons who were overweight/obese in early midlife had significantly lower cognitive performance across domains in late life and significantly steeper decline in perceptual speed, adjusting for cardio-metabolic factors. Both underweight and overweight/obesity in late midlife were associated with lower cognitive abilities in late life. However, the association between underweight and low cognitive abilities did not remain significant when weight decline between early and late midlife was controlled for.

Conclusion: There is a negative effect on cognitive abilities later in life related to being overweight/obese across midlife. Moreover, weight decline across midlife rather than low weight in late midlife per se was associated with low cognitive abilities. Weight patterns across midlife may be prodromal markers of late life cognitive health.

Ort, förlag, år, upplaga, sidor
Springer, 2013. Vol. 37, nr 2, s. 296-302
Nyckelord [en]
obesity overweight cognition life span old age aged
Nationell ämneskategori
Gerontologi, medicinsk/hälsovetenskaplig inriktning
Identifikatorer
URN: urn:nbn:se:hj:diva-17743DOI: 10.1038/ijo.2012.37ISI: 000316932100020PubMedID: 22450854Scopus ID: 2-s2.0-84873722966Lokalt ID: HHJÅldrandeISOAI: oai:DiVA.org:hj-17743DiVA, id: diva2:506875
Tillgänglig från: 2012-03-01 Skapad: 2012-03-01 Senast uppdaterad: 2019-04-09Bibliografiskt granskad

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Dahl, AnnaFransson, Eleonor

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Dahl, AnnaFransson, Eleonor
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HHJ, Institutet för gerontologiHHJ. Åldrande - livsvillkor och hälsaHHJ, Avd. för naturvetenskap och biomedicin
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International Journal of Obesity
Gerontologi, medicinsk/hälsovetenskaplig inriktning

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