Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly.Show others and affiliations
2006 (English)In: Journal of Immunology, ISSN 0022-1767, E-ISSN 1550-6606, Vol. 176, no 4, p. 2645-2653Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2006. Vol. 176, no 4, p. 2645-2653
Keywords [en]
Aged; 80 and over, Aging/*immunology, CD4-Positive T-Lymphocytes/immunology, CD8-Positive T-Lymphocytes/cytology/*immunology/*pathology, Clone Cells/cytology/immunology, Cytomegalovirus/*immunology, Cytomegalovirus Infections/*immunology/*mortality/virology, Female, Humans, Interferon Type II/secretion, Longitudinal Studies, Male, Phenotype, Receptors; Antigen; T-Cell/immunology
National Category
Other Social Sciences not elsewhere specified
Identifiers
URN: urn:nbn:se:hj:diva-4282PubMedID: 16456027OAI: oai:DiVA.org:hj-4282DiVA, id: diva2:35102
2007-10-312007-10-312017-12-12Bibliographically approved