It is believed that workplace creativity and innovation are fostered by positive leader behaviours and positive workplace relationships and hindered by the opposite. However, some challenge this view, arguing that creativity and innovation can actually be fostered when employees experience what is increasingly referred to as the dark side of leadership and workplace mistreatment. Research on this area is sparse, contradictory and overly confusing. We begin by defining the dark side of leadership and then provide a comprehensive systematic review of 145 empirical studies on the topic. We review research on a broad range of constructs related to leadership and workplace mistreatment, such as abusive supervision, authoritarian leadership, destructive leadership, narcissistic leadership and relationship conflict. Our review reports the main effects, summarizes the results of the mediating and moderating variables, and highlights methodological shortcomings of the past literature. On this basis, several recommendations are made to advance this field of research.