Effective team work is regarded as a key factor for success in missions performed by fighter aircraft in a Tactical Air Unit (TAU). Many factors contrib-ute to how a team will succeed in their mission. From the existing literature on teamwork, Salas, Sims and Burke [1], suggested five main factors and three sup-porting mechanisms for effective team work. These were proposed as the “Big Five” of teamwork. This article investigates if the model offered by Salas et al. is applicable to a TAU of fighter aircraft. Semi-structured interviews were carried out with six fighter pilots. The results of these interviews imply that the model has relevance for the teamwork in a TAU. Moreover, this paper discusses impli-cations for the design of future decision-support systems that support team effec-tiveness.