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Prevalence of cervical infection and genotype distribution of human Papilloma virus among females in Da Nang, Vietnam
Department of Medical Laboratory, Da Nang University of Medical Technology and Pharmacy, Da Nang, Vietnam.
Department of Medical Laboratory, Da Nang University of Medical Technology and Pharmacy, Da Nang, Vietnam.
Högskolan i Jönköping, Hälsohögskolan, HHJ, Avd. för naturvetenskap och biomedicin.ORCID-id: 0000-0003-2328-7334
Karolinska University Laboratory, Karolinska University Hospital, Stockholm, Sweden.
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2017 (Engelska)Ingår i: Anticancer Research, ISSN 0250-7005, E-ISSN 1791-7530, Vol. 37, nr 3, s. 1243-1247Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Aim: The goal of the present study was to determine the prevalence and distribution of high-risk human papilloma virus (HPV) genotypes in women from two districts in and around Da Nang city, Vietnam.

Materials and Methods: All participants were randomly selected, 200 from the Hai Chau district and 200 from the Son Tra district. The detection and genotyping of HPV were performed by real-time polymerase chain reaction (PCR) technique.

Results: Out of a total of 400 women, we found that 38 (9.5%) were infected with a high-risk HPV genotype, the most prevalent genotypes being 16, 18, 58 and 59. By assessment of the HPV findings in relation to sociodemographic characteristics, we found significant differences between the two study districts and between the age groups, as well as differences associated with occupation and the use of contraceptives.

Conclusion: The proportion of high–risk genotypes other than 16 and 18 was relatively high, and since the HPV genotype distribution is known to vary greatly across populations, the information from this study can be used for planning of screening and vaccination programs in Da Nang.

Ort, förlag, år, upplaga, sidor
International Institute of Anticancer Research , 2017. Vol. 37, nr 3, s. 1243-1247
Nyckelord [en]
Cervical cancer; human papilloma virus; high-risk HPV genotype; prevalence; Vietnam
Nationell ämneskategori
Cancer och onkologi
Identifikatorer
URN: urn:nbn:se:hj:diva-35221DOI: 10.21873/anticanres.11440ISI: 000397129600037PubMedID: 28314288Scopus ID: 2-s2.0-85015964342OAI: oai:DiVA.org:hj-35221DiVA, id: diva2:1083218
Tillgänglig från: 2017-03-20 Skapad: 2017-03-20 Senast uppdaterad: 2019-12-20Bibliografiskt granskad

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Dimberg, Jan

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