Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Sublingual administration of atropine eyedrops in children with excessive drooling - a pilot study
Högskolan i Jönköping, Hälsohögskolan, HHJ. CHILD. National Oral Disability Centre for Rare Disorders, The Institute for Postgraduate Dental Education, Jönköping, Sweden.
Department of Otorhinolaryngology and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Department of Dentofacial Orthopedics, Maxillofacial Unit, Linköping University, Linköping, Sweden.
Habilitation Centre, Ryhov County Hospital, Jönköping, Sweden.
Visa övriga samt affilieringar
2017 (Engelska)Ingår i: International Journal of Paediatric Dentistry, ISSN 0960-7439, E-ISSN 1365-263X, Vol. 27, nr 1, s. 22-29Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

BACKGROUND: Drooling can be a severe disability and have high impact on daily life. Reversible treatment is preferable.

AIM: To analyse whether sublingual administration of atropine eyedrops is a useful reversible treatment option for severe drooling in children with disabilities.

DESIGN: The study had a prospective, single-system research design. The participants served as their own controls. The study period was 3 weeks without treatment, 4 weeks with atropine eyedrop solution 10 mg/mL one drop a day followed by 4 weeks of one drop twice a day. Parents' rating of their child's drooling was assessed on a 100-mm VAS, and unstimulated salivary secretion rate measurement was performed together with notations about side effects and practicality.

RESULTS: Parents' VAS assessment of drooling decreased from a median (range) of 74 (40-98) at baseline to 48 (18-88) (P = 0.05) and 32 (12-85) (P = 0.004) after 4 weeks of atropine once a day and another 4 weeks of atropine twice a day, respectively (n = 11). Unstimulated salivary secretion rates decreased from baseline to end of study (P = 0.032). Several parents complained about difficult administration. No irreversible side effects were noted.

CONCLUSIONS: Sublingual atropine eyedrops may be an alternative for treatment of severe drooling in children with disabilities.

Ort, förlag, år, upplaga, sidor
Wiley-Blackwell, 2017. Vol. 27, nr 1, s. 22-29
Nationell ämneskategori
Odontologi
Identifikatorer
URN: urn:nbn:se:hj:diva-34166DOI: 10.1111/ipd.12219ISI: 000389925200005PubMedID: 26708211Scopus ID: 2-s2.0-84952909969OAI: oai:DiVA.org:hj-34166DiVA, id: diva2:1051958
Forskningsfinansiär
Forskningsrådet i Sydöstra Sverige, FORSSRegion ÖstergötlandTillgänglig från: 2016-12-05 Skapad: 2016-12-05 Senast uppdaterad: 2017-12-18Bibliografiskt granskad

Open Access i DiVA

Fulltext(305 kB)98 nedladdningar
Filinformation
Filnamn FULLTEXT02.pdfFilstorlek 305 kBChecksumma SHA-512
89763fa2943298a4a38c34f47a34cdd7b59ddc63f341d4637aa09f42882c2878435db39c175b1fdaffdf5769d9d7a5ea992f0a6f74770ce444fcd7f84a915b7c
Typ fulltextMimetyp application/pdf

Övriga länkar

Förlagets fulltextPubMedScopus

Personposter BETA

Norderyd, Johanna

Sök vidare i DiVA

Av författaren/redaktören
Norderyd, Johanna
Av organisationen
HHJ. CHILD
I samma tidskrift
International Journal of Paediatric Dentistry
Odontologi

Sök vidare utanför DiVA

GoogleGoogle Scholar
Totalt: 109 nedladdningar
Antalet nedladdningar är summan av nedladdningar för alla fulltexter. Det kan inkludera t.ex tidigare versioner som nu inte längre är tillgängliga.

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 197 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf