Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Association of current and former smoking with body mass index: A study of smoking discordant twin pairs from 21 twin cohorts
Vise andre og tillknytning
2018 (engelsk)Inngår i: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 13, nr 7, artikkel-id e0200140Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Background Smokers tend to weigh less than never smokers, while successful quitting leads to an increase in body weight. Because smokers and non-smokers may differ in genetic and environmental family background, we analysed data from twin pairs in which the co-twins differed by their smoking behaviour to evaluate if the association between smoking and body mass index (BMI) remains after controlling for family background.

Methods and findings

The international CODATwins database includes information on smoking and BMI measured between 1960 and 2012 from 156,593 twin individuals 18–69 years of age. Individual-based data (230,378 measurements) and data of smoking discordant twin pairs (altogether 30,014 pairwise measurements, 36% from monozygotic [MZ] pairs) were analysed with linear fixed-effects regression models by 10-year periods. In MZ pairs, the smoking co-twin had, on average, 0.57 kg/m2 lower BMI in men (95% confidence interval (CI): 0.49, 0.70) and 0.65 kg/m2 lower BMI in women (95% CI: 0.52, 0.79) than the never smoking co-twin. Former smokers had 0.70 kg/m2 higher BMI among men (95% CI: 0.63, 0.78) and 0.62 kg/ m2 higher BMI among women (95% CI: 0.51, 0.73) than their currently smoking MZ co-twins. Little difference in BMI was observed when comparing former smoking co-twins with their never smoking MZ co-twins (0.13 kg/m2, 95% CI 0.04, 0.23 among men; -0.04 kg/m2, 95% CI -0.16, 0.09 among women). The associations were similar within dizygotic pairs and when analysing twins as individuals. The observed series of cross-sectional associations were independent of sex, age, and measurement decade.

Conclusions

Smoking is associated with lower BMI and smoking cessation with higher BMI. However, the net effect of smoking and subsequent cessation on weight development appears to be minimal, i.e. never more than an average of 0.7 kg/m2 

sted, utgiver, år, opplag, sider
Public Library of Science , 2018. Vol. 13, nr 7, artikkel-id e0200140
Emneord [en]
adult, aged, article, body mass, controlled study, female, human, major clinical study, male, remission, smoking cessation
HSV kategori
Identifikatorer
URN: urn:nbn:se:hj:diva-41670DOI: 10.1371/journal.pone.0200140ISI: 000438457400025PubMedID: 30001359Scopus ID: 2-s2.0-85049777857Lokal ID: HHJARNISOAI: oai:DiVA.org:hj-41670DiVA, id: diva2:1252210
Tilgjengelig fra: 2018-10-01 Laget: 2018-10-01 Sist oppdatert: 2018-11-01bibliografisk kontrollert

Open Access i DiVA

Fulltext(1585 kB)54 nedlastinger
Filinformasjon
Fil FULLTEXT01.pdfFilstørrelse 1585 kBChecksum SHA-512
7ea5a0836c18fbc333ae7e4e3937692144fac386df425cee3f1351ada4ae225fa04609aeee34ce28eef7f394efd478962507fb944a2d5537065f348b9c56f2d9
Type fulltextMimetype application/pdf

Andre lenker

Forlagets fulltekstPubMedScopus

Personposter BETA

Dahl Aslan, Anna K.

Søk i DiVA

Av forfatter/redaktør
Dahl Aslan, Anna K.
Av organisasjonen
I samme tidsskrift
PLoS ONE

Søk utenfor DiVA

GoogleGoogle Scholar
Totalt: 54 nedlastinger
Antall nedlastinger er summen av alle nedlastinger av alle fulltekster. Det kan for eksempel være tidligere versjoner som er ikke lenger tilgjengelige

doi
pubmed
urn-nbn

Altmetric

doi
pubmed
urn-nbn
Totalt: 59 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf