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Rundqvist, Louise
Publications (2 of 2) Show all publications
Rundqvist, L., Engvall, J., Faresjö, M. & Blomstrand, P. (2018). Left ventricular diastolic function is enhanced after peak exercise in endurance-trained adolescents as well as in their non-trained controls. Clinical Physiology and Functional Imaging, 38(6), 1054-1061
Open this publication in new window or tab >>Left ventricular diastolic function is enhanced after peak exercise in endurance-trained adolescents as well as in their non-trained controls
2018 (English)In: Clinical Physiology and Functional Imaging, ISSN 1475-0961, E-ISSN 1475-097X, Vol. 38, no 6, p. 1054-1061Article in journal (Refereed) Published
Abstract [en]

The aims of the study were to explore the temporal change of cardiac function after peak exercise in adolescents, and to investigate how these functional changes relate to maximal oxygen uptake (VO2max ). The cohort consisted of 27 endurance-trained adolescents aged 13-19 years, and 27 controls individually matched by age and gender. Standard echocardiography and colour tissue Doppler were performed at rest, and immediately after as well as 15 min after a maximal cardio pulmonary exercise test (CPET) on a treadmill. The changes in systolic and diastolic parameters after exercise compared to baseline were similar in both groups. The septal E/e'-ratio increased immediately after exercise in both the active and the control groups (from 9·2 to 11·0; P<0·001, and from 8·7 to 10·2; P = 0·008, respectively). In a comparison between the two groups after CPET, the septal E/e'-ratio was higher in the active group both immediately after exercise and 15 min later compared to the control group (P = 0·007 and P = 0·006, respectively). We demonstrated a positive correlation between VO2max and cardiac function including LVEF and E/e' immediately after CPET, but the strongest correlation was found between VO2max and LVEDV (r = 0·67, P<0·001) as well as septal E/e' (r = 0·34, P = 0·013). Enhanced diastolic function was found in both groups, but this was more pronounced in active adolescents. The cardiac functional response to exercise, in terms of LVEF and E/e', correlates with the increase in VO2 uptake. These findings in trained as well as un-trained teenagers have practical implications when assessing cardiac function.

Place, publisher, year, edition, pages
John Wiley & Sons, 2018
Keywords
E/e′, diastolic function, echocardiography, heart, systolic function, training, youngster
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:hj:diva-41801 (URN)10.1111/cpf.12534 (DOI)000446073500019 ()29947056 (PubMedID)2-s2.0-85054186924 (Scopus ID)
Available from: 2018-10-10 Created: 2018-10-10 Last updated: 2018-10-19Bibliographically approved
Rundqvist, L., Engvall, J., Faresjö, M., Carlsson, E. & Blomstrand, P. (2017). Regular endurance training in adolescents impacts atrial and ventricular size and function. European Heart Journal Cardiovascular Imaging, 18(6), 681-687
Open this publication in new window or tab >>Regular endurance training in adolescents impacts atrial and ventricular size and function
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2017 (English)In: European Heart Journal Cardiovascular Imaging, ISSN 2047-2404, E-ISSN 2047-2412, Vol. 18, no 6, p. 681-687Article in journal (Refereed) Published
Abstract [en]

Aims: The aims of the study were to explore the effects of long-term endurance exercise on atrial and ventricular size and function in adolescents and to examine whether these changes are related to maximal oxygen uptake (VO2max).

Methods and results: Twenty-seven long-term endurance-trained adolescents aged 13–19 years were individually matched by age and gender with 27 controls. All participants, 22 girls and 32 boys, underwent an echocardiographic examination at rest, including standard and colour tissue Doppler investigation. VO2max was assessed during treadmill exercise. All heart dimensions indexed for body size were larger in the physically active group compared with controls: left ventricular end-diastolic volume 60 vs. 50 mL/m2 (P <0.001), left atrial volume 27 vs. 19 mL/m2 (P <0.001), and right ventricular (RV) and right atrial area 15 vs. 13 and 9 vs. 7 cm2/m2, respectively (P <0.001 for both). There were strong associations between the size of the cardiac chambers and VO2max. Further, we found improved systolic function in the active group compared with controls: left ventricular ejection fraction 61 vs. 59% (P= 0.036), tricuspid annular plane systolic excursion 12 vs. 10 mm/m2 (P= 0.008), and RV early peak systolic velocity s′ 11 vs. 10 cm/s (P = 0.031).

Conclusion: Cardiac remodelling to long-term endurance exercise in adolescents is manifested by an increase in atrial as well as ventricular dimensions. The physically active group also demonstrated functional remodelling with an increase in TAPSE and systolic RV wall velocity. These findings have practical implications when assessing cardiac enlargement and function in physically active youngsters.

Place, publisher, year, edition, pages
Oxford University Press, 2017
Keywords
Echocardiography; Heart; Athlete; Atria; Adolescent; Exercise
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:hj:diva-34670 (URN)10.1093/ehjci/jew150 (DOI)000405182500014 ()27406576 (PubMedID)2-s2.0-85029069005 (Scopus ID)
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Available from: 2017-01-11 Created: 2017-01-11 Last updated: 2017-09-25Bibliographically approved
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