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Saffari, M., Lin, C.-Y., Koenig, H. G., O’Garo, K.-G. N., Broström, A. & Pakpour, A. H. (2019). A Persian version of the Affiliate Stigma Scale in caregivers of people with dementia. Health Promotion Perspectives, 9(1), 31-39
Open this publication in new window or tab >>A Persian version of the Affiliate Stigma Scale in caregivers of people with dementia
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2019 (English)In: Health Promotion Perspectives, ISSN 2228-6497, Vol. 9, no 1, p. 31-39Article in journal (Refereed) Published
Abstract [en]

Background:

Dementia is prevalent among older adults and frequently causes dependence on family caregivers. Caregivers may experience a form of stigmatization called affiliate stigma that negatively affects their mental health. The current study sought to establish the psychometric properties of a tool to measure affiliate stigma among Iranian caregivers.

Methods:

Overall, 541 caregivers of older people with dementia were included in this cross-sectional study. Several measures were used to assess the psychometric properties of the Affiliate Stigma Scale (ASS) including the Zarit Burden Interview (ZBI), Hospital Anxiety and Depression Scale (HADS), Short Form 12 (SF-12), Rosenberg Self-Esteem Scale (RSES), and Multidimensional Scale of Perceived Social Support (MSPSS). Convergent and discriminate validity were examined. Exploratory and confirmatory factor analyses were utilized to assess the factor structure of the ASS and a Rasch model was used to evaluate the measurement functioning of the scale.

Results:

Factor loadings ranged from 0.69 to 0.83 and test-retest reliability from 0.72 to 0.89. Item difficulty ranged widely from -0.66 to 0.89. No considerable differential item functioning (DIF) was found across gender. Confirmatory factor analysis confirmed the three cognitive, affective, and behavioral dimensions of the scale (comparative fit index [CFI]=0.931 to 0.995, root mean square error of approximation [RMSEA]=0.046 to 0.068). Internal consistency was acceptable (Cronbach’s alpha: 0.88 to 0.94). Significant and positive relationships were found between affiliate stigma and depression, anxiety, and caregiving burden (beta = 0.35 to 0.46).

Conclusion:

The ASS is a psychometrically valid measure for assessing affiliate stigma in Iranian caregivers of people with dementia. Application of this tool among other caregivers, languages and cultures deserves further study.

Place, publisher, year, edition, pages
Tabriz University of Medical Sciences, 2019
Keywords
Stigma, Family caregivers, Dementia, Psychometrics
National Category
Nursing
Identifiers
urn:nbn:se:hj:diva-43112 (URN)10.15171/hpp.2019.04 (DOI)000456575000004 ()30788265 (PubMedID)2-s2.0-85065551653 (Scopus ID)POA HHJ;HHJADULTIS (Local ID)POA HHJ;HHJADULTIS (Archive number)POA HHJ;HHJADULTIS (OAI)
Available from: 2019-02-20 Created: 2019-02-20 Last updated: 2019-06-12Bibliographically approved
Sanaeinasab, H., Saffari, M., Dashtaki, M.-a., Pakpour, A. H., Karimi Zarchi, A., O'Garo, K.-G. N. & Koenig, H. G. (2019). A theory of planned behavior-based program to increase physical activity in overweight/obese military personnel: A randomised controlled trial. Applied Psychology: Health and Well-Being
Open this publication in new window or tab >>A theory of planned behavior-based program to increase physical activity in overweight/obese military personnel: A randomised controlled trial
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2019 (English)In: Applied Psychology: Health and Well-Being, ISSN 1758-0846, E-ISSN 1758-0854Article in journal (Refereed) Epub ahead of print
Abstract [en]

Background: Designing a health promotion program to increase physical activity may contribute to weight management. The purpose of this study was to investigate a theory of planned behavior (TPB) program to address this problem in military people.

Methods: Eighty-four obese/overweight military personnel were randomised into the intervention or control group. A questionnaire assessed demographics, aspects of the TPB program, and physical activity levels. Also assessed were blood glucose and lipid levels. The intervention consisted of seven educational sessions based on TPB. Data were collected at baseline and 3 months after the intervention.

Results: All constructs of the TPB improved between baseline and follow-up in the intervention group (p <.001), while there were no significant changes in the control group (within-group comparisons). Between-group comparisons on TPB measures revealed differences in all domains when results were controlled for baseline covariates. Greater light and moderate physical activity was observed in the intervention group. Body mass index decreased significantly within the intervention group (p <.001). Changes in triglyceride and high-density lipoprotein also favored the intervention over the control group.

Conclusion: An intervention based on the TPB may be effective in promoting physical activity and decreasing weight in military personnel who are obese or overweight. 

Place, publisher, year, edition, pages
John Wiley & Sons, 2019
Keywords
health education, military, obesity, physical activity
National Category
Applied Psychology
Identifiers
urn:nbn:se:hj:diva-45597 (URN)10.1111/aphw.12175 (DOI)31353846 (PubMedID)2-s2.0-85070297944 (Scopus ID);HHJÖvrigtIS (Local ID);HHJÖvrigtIS (Archive number);HHJÖvrigtIS (OAI)
Available from: 2019-08-19 Created: 2019-08-19 Last updated: 2019-08-19
Lin, C.-Y., Cheng, A. S. K., Nejati, B., Imani, V., Ulander, M., Browall, M., . . . Pakpour, A. H. (2019). A thorough psychometric comparison between Athens Insomnia Scale and Insomnia Severity Index among patients with advanced cancer. Journal of Sleep Research, Article ID e12891.
Open this publication in new window or tab >>A thorough psychometric comparison between Athens Insomnia Scale and Insomnia Severity Index among patients with advanced cancer
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2019 (English)In: Journal of Sleep Research, ISSN 0962-1105, E-ISSN 1365-2869, article id e12891Article in journal (Refereed) Epub ahead of print
Abstract [en]

For patients with cancer, sleep disturbance is commonplace. Using classical test theory and Rasch analyses, the present study compared two commonly used psychometric instruments for insomnia – Athens Insomnia Scale and Insomnia Severity Index – among patients with advanced cancer. Through convenience sampling, patients with cancer at stage III or IV (n = 573; 326 males; mean age = 61.3 years; SD = 10.7) from eight oncology units of university hospitals in Iran participated in the study. All the participants completed the Athens Insomnia Scale, Insomnia Severity Index, Edmonton Symptom Assessment Scale, Hospital Anxiety and Depression Scale, General Health Questionnaire-12, Epworth Sleepiness Scale and Pittsburgh Sleep Quality Index. Additionally, 433 participants wore an Actigraph device for two continuous weekdays. Classical test theory and Rasch analysis both supported the construct validity for Athens Insomnia Scale (factor loadings from confirmatory factor analysis = 0.61–0.87; test–retest reliability = 0.72–0.82; infit mean square = 0.81–1.17; outfit MnSq = 0.79–1.14) and for Insomnia Severity Index (factor loadings from confirmatory factor analysis = 0.61–0.81; test–retest reliability = 0.72–0.82; infit mean square = 0.72–1.14; outfit mean square = 0.76–1.11). Both Athens Insomnia Scale and Insomnia Severity Index had significant associations with Edmonton Symptom Assessment Scale, Hospital Anxiety and Depression Scale, General Health Questionnaire-12, Epworth Sleepiness Scale and Pittsburgh Sleep Quality Index, as well as having good sensitivity and specificity. Significant differences in the actigraphy measure were found between insomniacs and non-insomniacs based on Athens Insomnia Scale or Insomnia Severity Index score. With promising results, healthcare providers can use either Athens Insomnia Scale or Insomnia Severity Index to understand the insomnia of patients with advanced cancer. 

Place, publisher, year, edition, pages
John Wiley & Sons, 2019
Keywords
confirmatory factor analysis, insomnia, oncology, psychometrics, Rasch analysis, sleep disorders
National Category
Neurology
Identifiers
urn:nbn:se:hj:diva-45538 (URN)10.1111/jsr.12891 (DOI)31328319 (PubMedID)2-s2.0-85069828622 (Scopus ID);HHJADULTIS (Local ID);HHJADULTIS (Archive number);HHJADULTIS (OAI)
Available from: 2019-08-12 Created: 2019-08-12 Last updated: 2019-08-12
Saffari, M., Sanaeinasab, H., Masoumbeigi, H., Pakpour, A. H., O'Garo, K. N. & Koenig, H. G. (2019). An Education-Based Text Messaging Program to Improve Nurses' Knowledge, Attitude, and Practice Related to Nosocomial Infections in Intensive Care Settings. Journal of Continuing Education in Nursing: Continuing Competence for the Future, 50(5), 211-217
Open this publication in new window or tab >>An Education-Based Text Messaging Program to Improve Nurses' Knowledge, Attitude, and Practice Related to Nosocomial Infections in Intensive Care Settings
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2019 (English)In: Journal of Continuing Education in Nursing: Continuing Competence for the Future, ISSN 0022-0124, E-ISSN 1938-2472, Vol. 50, no 5, p. 211-217Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Nosocomial infection (NI) is common in health care settings. Educational strategies such as mobile teaching methods for health care providers may help to resolve this problem. This pilot study assessed the influence of a text messaging program to improve intensive care unit nurses' knowledge, attitude, and practice related to NI prevention.

METHOD: In this single-group experimental study, 32 nurses received an educational intervention via short text messages on their cell phones. Information on knowledge, attitude, and practice regarding NI prevention was collected using a standard scale. Preventive messages about NI were prepared and sent to participants during a 2-month trial. Results were assessed 2 weeks after the intervention, and data were analyzed by paired t test.

RESULTS: Knowledge, attitude, and practice of participants increased by 17%, 3%, and 9%, respectively, from baseline to follow up. The average score on the knowledge dimension was lower than for other components. Knowledge components such as hand hygiene, work safety, and protective equipment increased to a lesser degree from pre- to posttest, compared with other aspects (p < .05 versus p < .001).

CONCLUSION: An education-based program operating through short text messages may be a useful in-service training strategy for intensive care unit nurses.

Place, publisher, year, edition, pages
Slack, 2019
National Category
Nursing
Identifiers
urn:nbn:se:hj:diva-44179 (URN)10.3928/00220124-20190416-07 (DOI)000466075600007 ()31026321 (PubMedID)2-s2.0-85065297395 (Scopus ID)HHJÖvrigtIS (Local ID)HHJÖvrigtIS (Archive number)HHJÖvrigtIS (OAI)
Available from: 2019-06-07 Created: 2019-06-07 Last updated: 2019-06-07Bibliographically approved
Tsai, M.-C., Strong, C., Latner, J. D., Lin, Y.-C., Pakpour, A. H., Lin, C.-Y. & Wang, S.-M. (2019). Attitudes toward and beliefs about obese persons across Hong Kong and Taiwan: wording effects and measurement invariance. Health and Quality of Life Outcomes, 17(1), Article ID 134.
Open this publication in new window or tab >>Attitudes toward and beliefs about obese persons across Hong Kong and Taiwan: wording effects and measurement invariance
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2019 (English)In: Health and Quality of Life Outcomes, ISSN 1477-7525, E-ISSN 1477-7525, Vol. 17, no 1, article id 134Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: The psychosocial consequences of obesity are important but often underrated. The Attitudes Toward Obese Persons (ATOP) and Beliefs About Obese Persons (BAOP) scales used to measure weight-related bias have little psychometric information, especially in East Asian contexts. The objective of this study was to use rigorous statistical methods to demonstrate the psychometric properties of these two instruments in Hong Kong and Taiwanese college students.

METHODS: A convenience sample of 707 students was recruited from the universities in Hong Kong and Taiwan. Several competing confirmatory factor analyses (CFAs) were conducted to confirm the factorial structure of the ATOP and BAOP. The best fit models for the ATOP and BAOP were chosen for the examination of the measurement invariance across subcultures. We then compared configurable models with or without loading and/or intercept constrained before correlating the latent constructs between the best models for the ATOP and BAOP.

RESULTS: The comparison in multiple CFAs found that the model with one factor and two correlated-wording-method factors outperformed the other models for both the ATOP and BOAP. However, the internal consistency was suboptimal (ATOP: α = .56 to .80; BTOP: α = .57 to .65) and the measurement invariance was somewhat unsupported among the Hong Kong and Taiwan samples. Moreover, after controlling wording effects, the latent construct of the ATOP was moderately associated with that of BAOP (r = .356; p < .001).

CONCLUSION: Chinese versions of the ATOP and BAOP can be treated as a unidimensional factor for use in Hong Kong and Taiwan university students. However, further refinements of both instruments may be needed before using them to capture the social attitudes and beliefs toward obesity individuals, which is expected to advance our understanding of weight-related bias in East Asian contexts.

Place, publisher, year, edition, pages
BioMed Central, 2019
Keywords
Cross-culture, Psychometrics, Weight bias, Weight stigma, Young adults
National Category
Nursing
Identifiers
urn:nbn:se:hj:diva-45567 (URN)10.1186/s12955-019-1198-6 (DOI)000477963600002 ()31362763 (PubMedID)GOA HHJ 2019;HHJÖvrigtIS (Local ID)GOA HHJ 2019;HHJÖvrigtIS (Archive number)GOA HHJ 2019;HHJÖvrigtIS (OAI)
Available from: 2019-08-15 Created: 2019-08-15 Last updated: 2019-08-15Bibliographically approved
Ericsson, C., Skagerström, J., Schildmeijer, K., Årestedt, K., Broström, A., Pakpour, A. H. & Nilsen, P. (2019). Can patients contribute to safer care in meetings with healthcare professionals? A cross-sectional survey of patient perceptions and beliefs.. BMJ Quality and Safety, 28(8), 657-666, Article ID bmjqs-2018-008524.
Open this publication in new window or tab >>Can patients contribute to safer care in meetings with healthcare professionals? A cross-sectional survey of patient perceptions and beliefs.
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2019 (English)In: BMJ Quality and Safety, ISSN 2044-5415, E-ISSN 2044-5423, Vol. 28, no 8, p. 657-666, article id bmjqs-2018-008524Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: To investigate patients' perceptions of their meetings with healthcare professionals and the extent to which they believe they can influence patient safety in these meetings.

DESIGN: Cross-sectional survey of patients using a study-specific questionnaire. Data were analysed using both parametric and non-parametric statistics.

SETTING: The study was conducted in primary and secondary care in three county councils in southeast Sweden by means of a survey questionnaire despatched in January 2017.

PARTICIPANTS: Survey data were collected from 1445 patients, 333 of whom were complainants (patients who had filed a complaint about being harmed in healthcare) and 1112 regular patients (patients recruited from healthcare units).

MAIN OUTCOME MEASURES: Patients' perceptions of meetings with physicians and nurses, beliefs concerning patients' contributions to safer care and whether the patients had suffered harm in healthcare during the past 10 years.

RESULTS: Most respondents reported that it was easy to ask physicians and nurses questions (84.9% and 86.6%) and to point out if something felt odd in their care (77.7% and 80.7%). In general, complainants agreed to a higher extent compared with regular patients that patients can contribute to safer care (mean 1.92 and 2.13, p<0.001). Almost one-third (31.2%) of the respondents (both complainants and regular patients) reported that they had suffered harm in healthcare during the past 10 years.

CONCLUSIONS: Most respondents believed that healthcare professionals can facilitate patient interaction and increase patient safety by encouraging patients to ask questions and take an active part in their care. Further research will need to identify strategies to support such questioning in routine practice and ensure that it achieves its intended goals.

Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2019
Keywords
adverse events, epidemiology and detection, medical error, measurement/epidemiology, patient safety, patient satisfaction
National Category
Health Care Service and Management, Health Policy and Services and Health Economy Nursing
Identifiers
urn:nbn:se:hj:diva-44175 (URN)10.1136/bmjqs-2018-008524 (DOI)000477894500008 ()31018984 (PubMedID)2-s2.0-85065298242 (Scopus ID)HOA HHJ 2019;HHJÖvrigtIS (Local ID)HOA HHJ 2019;HHJÖvrigtIS (Archive number)HOA HHJ 2019;HHJÖvrigtIS (OAI)
Available from: 2019-06-07 Created: 2019-06-07 Last updated: 2019-08-09Bibliographically approved
Nejati, B., Lin, C.-C., Aaronson, N. K., Cheng, A. S. K., Browall, M., Lin, C.-Y., . . . Pakpour, A. H. (2019). Determinants of satisfactory patient communication and shared decision making in patients with multiple myeloma. Psycho-Oncology, 28(7), 1490-1497
Open this publication in new window or tab >>Determinants of satisfactory patient communication and shared decision making in patients with multiple myeloma
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2019 (English)In: Psycho-Oncology, ISSN 1057-9249, E-ISSN 1099-1611, Vol. 28, no 7, p. 1490-1497Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: To identify determinants of shared decision making in patients with multiple myeloma (MM) to facilitate the design of a program to maximize the effects of shared decision making.

METHODS: This prospective longitudinal study recruited 276 adult patients (52% male, mean age 62.86 y, SD 15.45). Each patient completed the eHealth Literacy Scale (eHEALS), Multidimensional Trust in Health Care Systems Scale (MTHCSS), Patient Communication Pattern Scale (PCPS), and 9-Item Shared Decision-Making Questionnaire (SDM-Q-9) at baseline and the SDM-Q-9 again 6 months later. One family member of the patient completed the Family Decision-Making Self-Efficacy (FDMSE) at baseline. Structural equation modeling (SEM) was used to investigate the associations between eHealth literacy (eHEALS), trust in the health care system (MTHCSS), self-efficacy in family decision making (FDMSE), patient communication pattern (PCPS), and shared decision making (SDM-Q-9).

RESULTS: SEM showed satisfactory fit (comparative fit index = 0.988) and significant correlations between the following: eHealth literacy and trust in the health care system (β = 0.723, P < 0.001); eHealth literacy and patient communication pattern (β = 0.242, P < 0.001); trust in the health care system and patient communication pattern (β = 0.397, P < 0.001); self-efficacy in family decision making and patient communication pattern (β = 0.264, P < 0.001); eHealth literacy and shared decision making (β = 0.267, P < 0.001); and patient communication pattern and shared decision making (β = 0.349, P < 0.001).

CONCLUSIONS: Patient communication and eHealth literacy were found to be important determinants of shared decision making. These factors should be taken into consideration when developing strategies to enhance the level of shared decision making.

Place, publisher, year, edition, pages
John Wiley & Sons, 2019
Keywords
cancer, multiple myeloma, oncology, patient communication, shared decision making, structural equation modeling
National Category
Cancer and Oncology
Identifiers
urn:nbn:se:hj:diva-45078 (URN)10.1002/pon.5105 (DOI)31087365 (PubMedID)2-s2.0-85066822686 (Scopus ID);HHJADULTIS,HHJIMPROVEIS (Local ID);HHJADULTIS,HHJIMPROVEIS (Archive number);HHJADULTIS,HHJIMPROVEIS (OAI)
Available from: 2019-06-25 Created: 2019-06-25 Last updated: 2019-07-14Bibliographically approved
Miri, S. F., Javadi, M., Lin, C.-Y., Griffiths, M. D., Björk, M. & Pakpour, A. H. (2019). Effectiveness of cognitive-behavioral therapy on nutrition improvement and weight of overweight and obese adolescents: A randomized controlled trial. Diabetes & Metabolic syndrome: clinical Research & Reviews, 13(3), 2190-2197
Open this publication in new window or tab >>Effectiveness of cognitive-behavioral therapy on nutrition improvement and weight of overweight and obese adolescents: A randomized controlled trial
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2019 (English)In: Diabetes & Metabolic syndrome: clinical Research & Reviews, ISSN 1871-4021, E-ISSN 1878-0334, Vol. 13, no 3, p. 2190-2197Article in journal (Refereed) Published
Abstract [en]

Aim: To assess the effectiveness of a cognitive-behavioral treatment (CBT) program on weight reduction among Iranian adolescents who are overweight. Methods: Using a randomized controlled trial design, 55 adolescents who were overweight (mean [SD] age = 14.64 [1.69] years; zBMI = 2.18 [0.65]) were recruited in the CBT program and 55 in the treatment as usual (TAU; mean age = 14.88 [1.50]; zBMI = 2.09 [0.57]) group. All the participants completed several questionnaires (Child Dietary Self-Efficacy Scale; Weight Efficacy Lifestyle questionnaire; Physical Exercise Self-Efficacy Scale; Pediatric Quality of Life Inventory; and self-reported physical activity and diet) and had their anthropometrics measured (height, weight, waist and hip circumferences, and body fat). Results: The CBT group consumed significantly more fruits and juice, vegetables, and dairy in the 6-month follow-up as compared with the TAU group (p-values <0.001). The CBT group consumed significantly less sweet snacks, salty snacks, sweet drinks, sausages/processed meat, and oils in the six-month follow-up compared with the TAU group (p-values<0.001). Additionally, the waist circumference, BMI, waist-hip ratio, and fat mass were significantly decreased in the CBT group in the six-month follow-up compared with the TAU group (p-values<0.005). The CBT group significantly improved their psychosocial health, physical activity, and health-related quality of life (p-values<0.001). Conclusion: The CBT program showed its effectiveness in reducing weight among Iranian adolescents who were overweight. Healthcare providers may want to adopt this program to treat excess weight problems among adolescents. 

Place, publisher, year, edition, pages
Elsevier, 2019
Keywords
Adolescence, CBT, Nutrition, Obesity, Overweight
National Category
Nutrition and Dietetics
Identifiers
urn:nbn:se:hj:diva-44352 (URN)10.1016/j.dsx.2019.05.010 (DOI)000472598700078 ()31235156 (PubMedID)2-s2.0-85066156391 (Scopus ID)PP HHJ 2019 embargo 12;HHJCHILDIS (Local ID)PP HHJ 2019 embargo 12;HHJCHILDIS (Archive number)PP HHJ 2019 embargo 12;HHJCHILDIS (OAI)
Available from: 2019-06-11 Created: 2019-06-11 Last updated: 2019-07-12Bibliographically approved
Lin, C.-Y., Imani, V., Broström, A., Årestedt, K., Pakpour, A. H. & Griffiths, M. D. (2019). Evaluating the Psychometric Properties of the 7-Item Persian Game Addiction Scale for Iranian Adolescents.. Frontiers in Psychology, 10, Article ID 149.
Open this publication in new window or tab >>Evaluating the Psychometric Properties of the 7-Item Persian Game Addiction Scale for Iranian Adolescents.
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2019 (English)In: Frontiers in Psychology, ISSN 1664-1078, E-ISSN 1664-1078, Vol. 10, article id 149Article in journal (Refereed) Published
Abstract [en]

The 7-item Gaming Addiction Scale (GAS) is a brief instrument based on DSM criteria to assess gaming addiction. Although the psychometric properties of the GAS have been tested using classical test theory, its psychometric properties have never been tested using modern test theory (e.g., Rasch analysis). The present study used a large adolescent sample in Iran to test the psychometric properties of the Persian GAS through both classical test and modern test theories. Adolescents (n = 4442; mean age = 15.3 years; 50.3% males) were recruited from Qazvin, Iran. In addition to the GAS, all of them completed the following instruments: the nine-item Internet Gaming Disorder Scale-Short Form (IGDS-SF9), Depression Anxiety Stress Scale (DASS), Pittsburgh Sleep Quality Index (PSQI), and a generic quality of life instrument. Two weeks later, all participants completed the GAS again. Confirmatory factor analysis (CFA) and Rasch analysis were used to test the unidimensionality of the GAS. Pearson correlation coefficients were used to test the test-retest reliability, and a regression model was used to test the criterion-related validity of the GAS. Both CFA and Rasch analysis supported the unidimensionality of the GAS. Pearson correlations coefficients showed satisfactory test-retest reliability of the GAS (r = 0.78 to 0.86), and the regression model demonstrated the criterion-related validity of the GAS (β = 0.31 with IGDS-SF9; 0.41 with PSQI). Based on the results, the Persian GAS is a reliable and valid instrument for healthcare providers to assess the level of gaming addiction among Persian-speaking adolescents.

Place, publisher, year, edition, pages
Frontiers Media S.A., 2019
Keywords
Rasch model, adolescent gaming, confirmatory factor analysis, gaming addiction, online addiction
National Category
Psychology
Identifiers
urn:nbn:se:hj:diva-43223 (URN)10.3389/fpsyg.2019.00149 (DOI)000457845600002 ()30804841 (PubMedID)2-s2.0-85061038332 (Scopus ID)GOA HHJ 2019;HHJADULTIS (Local ID)GOA HHJ 2019;HHJADULTIS (Archive number)GOA HHJ 2019;HHJADULTIS (OAI)
Available from: 2019-03-01 Created: 2019-03-01 Last updated: 2019-03-01Bibliographically approved
Hamedi-Shahraki, S., Eshraghian, M.-R., Yekaninejad, M.-S., Nikoobakht, M., Rasekhi, A., Chen, H. & Pakpour, A. H. (2019). Health-related quality of life and medication adherence in elderly patients with epilepsy.. Neurologia i Neurochirurgia Polska, 53(2), 123-130
Open this publication in new window or tab >>Health-related quality of life and medication adherence in elderly patients with epilepsy.
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2019 (English)In: Neurologia i Neurochirurgia Polska, ISSN 0028-3843, E-ISSN 1897-4260, Vol. 53, no 2, p. 123-130Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: Considering the high prevalence of epilepsy in the elderly and the importance of maximising their quality of life (QoL), this study aimed to investigate the relationship between medication adherence and QoL, and the mediating effects of medication adherence on the association between serum antiepileptic drug (AED) level and seizure severity with QoL in elderly epileptics.

METHODS: In a longitudinal study, 766 elderly patients with epilepsy who were prescribed a minimum of one antiepileptic drug were selected by convenience sampling method. A Medication Adherence Report Scale (MARS-5) questionnaire was completed at the baseline. Seizure severity and QoL were assessed after six months using the Liverpool Seizure Severity Scale (LSSS) and the QoL in Epilepsy (QOLIE-31) questionnaires respectively. Serum level of AED was also measured at six-month follow-up.

RESULTS: Medication adherence was significantly correlated with both seizure severity (β = -0.33, p < 0.0001) and serum AED level (β = 0.29, p < 0.0001) after adjusting for demographic and clinical characteristics. Neither QoL nor its sub-classes were correlated with seizure severity. In addition, a significant correlation was not observed between serum AED level and QoL. However, medication adherence was significantly correlated with QoL (β = 0.30, p < 0.0001). The mediating effects of medication adherence on the association between serum AED level (Z = 3.39, p < 0.001) and seizure severity (Z = -3.47, p < 0.001) with QoL were supported by the Sobel test.

CONCLUSION: This study demonstrates that medication adherence has a beneficial impact on QoL in elderly epileptics. Therefore, adherence to treatment should be monitored to improve their QoL.

Keywords
elderly, epilepsy, medication adherence, quality of life, seizure
National Category
Social and Clinical Pharmacy Geriatrics Neurology
Identifiers
urn:nbn:se:hj:diva-44034 (URN)10.5603/PJNNS.a2019.0008 (DOI)000467692100003 ()30807640 (PubMedID)2-s2.0-85065881952 (Scopus ID)HOA HHJ 2019;HHJÖvrigtIS (Local ID)HOA HHJ 2019;HHJÖvrigtIS (Archive number)HOA HHJ 2019;HHJÖvrigtIS (OAI)
Available from: 2019-06-04 Created: 2019-06-04 Last updated: 2019-06-04Bibliographically approved
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ORCID iD: ORCID iD iconorcid.org/0000-0002-8798-5345

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