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Nilsson, Sven E
Alternative names
Publications (10 of 28) Show all publications
Nilsson, S., Fransson, E. & Brismar, K. (2009). Relationship between serum progesterone concentrations and cardiovascular disease, diabetes, and mortality in elderly Swedish men and women: An 8-year prospective study. Gender Medicine, 6(3), 433-443
Open this publication in new window or tab >>Relationship between serum progesterone concentrations and cardiovascular disease, diabetes, and mortality in elderly Swedish men and women: An 8-year prospective study
2009 (English)In: Gender Medicine, ISSN 1550-8579, Vol. 6, no 3, p. 433-443Article in journal (Refereed) Published
Place, publisher, year, edition, pages
Elsevier, 2009
National Category
Gerontology, specialising in Medical and Health Sciences
Identifiers
urn:nbn:se:hj:diva-8564 (URN)10.1016/j.genm.2009.09.011 (DOI)000270832300005 ()19850239 (PubMedID)2-s2.0-70349999252 (Scopus ID)
Available from: 2009-04-21 Created: 2009-04-21 Last updated: 2019-09-02Bibliographically approved
Malmberg, B., Nilsson, S. E., Fransson, E. & Brismar, K. (2008). Increased Serum Prolactin in Elderly is Associated with Worse Subjective Health, Higher Risk of Dementia and Impaired Survival. In: 19th Nordic Congress of Gerontology: .
Open this publication in new window or tab >>Increased Serum Prolactin in Elderly is Associated with Worse Subjective Health, Higher Risk of Dementia and Impaired Survival
2008 (English)In: 19th Nordic Congress of Gerontology, 2008Conference paper, Published paper (Other (popular science, discussion, etc.))
Identifiers
urn:nbn:se:hj:diva-5910 (URN)
Available from: 2008-08-18 Created: 2008-08-18 Last updated: 2009-04-21Bibliographically approved
Nilsson, S. E. (2008). Pulserande elektromagnetiska fält och placebo gav samma effekt. Läkartidningen, 105(32-33), 2167-2170
Open this publication in new window or tab >>Pulserande elektromagnetiska fält och placebo gav samma effekt
2008 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 105, no 32-33, p. 2167-2170Article in journal (Other (popular science, discussion, etc.)) Published
Identifiers
urn:nbn:se:hj:diva-5908 (URN)
Available from: 2008-08-15 Created: 2008-08-15 Last updated: 2017-12-12Bibliographically approved
Wikby, A., Månsson, I. A., Johansson, B., Strindhall, J. & Nilsson, S. E. (2008). The immune risk profile is associated with age and gender: findings from three Swedish population studies of individuals 20-100 years of age.. Biogerontology (Dordrecht), 9(5), 299-308
Open this publication in new window or tab >>The immune risk profile is associated with age and gender: findings from three Swedish population studies of individuals 20-100 years of age.
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2008 (English)In: Biogerontology (Dordrecht), ISSN 1389-5729, E-ISSN 1573-6768, Vol. 9, no 5, p. 299-308Article in journal (Refereed) Published
Abstract [en]

Earlier we identified an Immune Risk Profile (IRP) of very old individuals, 86-94 years of age, characterised by an inverted CD4/CD8 ratio and associated with persistent cytomegalovirus infection and an increase in the numbers of CD3+CD8+CD28- cells. In the present study we included data from a population-based sample in the age range of 20-79 years to examine the prevalence of individuals with an inverted CD4/CD8 ratio relative to age and gender across the entire adult lifespan. Immunological monitoring that was conducted included analysis of the numbers of T-cells in the subsets CD3+, CD3+CD4+, and CD3+CD8+ as well as CD3+CD8+CD28+, CD3+CD8+CD28-, and CD8+CD45RA+CCR7+. There was found to be a significant lowering of the numbers of CD3+, CD3+CD4+, and CD3+CD8+, and of the CD8+CD45RA+CCR7+ cells across the adult life-span. Notably, the prevalence of individuals with an inverted CD4/CD8 ratio increased from about 8% in the age range of 20-59 years to about 16% in the age range of 60-94 years. The mortality rate in individuals with an inverted CD4/CD8 ratio also increased significantly above the age of 60. Interestingly, the proportion of individuals with an inverted CD4/CD8 ratio was found to be significantly higher in men, whereas the numbers of CD3+CD4+ helper and CD8+CD45RA+CCR7+ naive cells and the CD4/CD8 ratio were found to be significantly higher in women. These results highlight the importance of functioning of the thymus in the development of IRP and may partly account for the differences between sexes in terms of longevity.

Place, publisher, year, edition, pages
Springer, 2008
Keywords
immune risk; T-cells; age; gender
National Category
Gerontology, specialising in Medical and Health Sciences
Identifiers
urn:nbn:se:hj:diva-7041 (URN)10.1007/s10522-008-9138-6 (DOI)000258653600002 ()18369735 (PubMedID)2-s2.0-50649111879 (Scopus ID)
Available from: 2008-12-10 Created: 2008-12-10 Last updated: 2019-09-02Bibliographically approved
Berg, S., Dahl, A. & Nilsson, S. (2007). Cognitive decline and dementia. In: Geropsychology: European perspectives for an aging world (pp. 165-182). Cambridge, Mass.: Hogrefe & Huber
Open this publication in new window or tab >>Cognitive decline and dementia
2007 (English)In: Geropsychology: European perspectives for an aging world, Cambridge, Mass.: Hogrefe & Huber , 2007, p. 165-182Chapter in book (Other (popular science, discussion, etc.))
Place, publisher, year, edition, pages
Cambridge, Mass.: Hogrefe & Huber, 2007
Identifiers
urn:nbn:se:hj:diva-3119 (URN)978-0-88937-340-2 (ISBN)
Available from: 2007-10-30 Created: 2007-10-30Bibliographically approved
Gold, C., Rovine, M., Nilsson, S., Berg, S., Malmberg, B. & McClearn, G. (2007). Gender and Patterns of Cardiovascular Diagnoses and Year of Diagnoses in an Unlike-Sex Twin Sample in Sweden. In: Gerontological Society of America 60th Annual Scientific Meeting: .
Open this publication in new window or tab >>Gender and Patterns of Cardiovascular Diagnoses and Year of Diagnoses in an Unlike-Sex Twin Sample in Sweden
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2007 (English)In: Gerontological Society of America 60th Annual Scientific Meeting, 2007Conference paper, Published paper (Refereed)
National Category
Other Social Sciences not elsewhere specified
Identifiers
urn:nbn:se:hj:diva-4738 (URN)
Available from: 2007-12-03 Created: 2007-12-03Bibliographically approved
Gold, C., Rovine, M., Nilsson, S., Berg, S., Malmberg, B. & McClearn, G. (2007). Gender and patterns of cardiovascular diagnoses in an unlike-sex twin sample in Sweden. In: The Gerontological Society of America, 60th Annual Scientific Meeting, San Francisco: (pp. 68-).
Open this publication in new window or tab >>Gender and patterns of cardiovascular diagnoses in an unlike-sex twin sample in Sweden
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2007 (English)In: The Gerontological Society of America, 60th Annual Scientific Meeting, San Francisco, 2007, p. 68-Conference paper, Published paper (Refereed)
Abstract [en]

Gender and Patterns of Cardiovascular Diagnoses and Year of Diagnoses in an Unlike-Sex Twin Sample in Sweden

Cardiovascular disease is the number one cause of death for men and women. This study examined diagnoses in health records in a sample of older-unlike-sex twins in Sweden (N=249 pairs). A physician in Sweden has examined these twins’ medical records going back as far as 50 years and compiled a database with diagnoses based on ICD-10 codes and the year of diagnosis. A subsample of twinpairs was created in which both members had been diagnosed with at least one cardiovascular condition (N=140 pairs). The number of these conditions ranged from 1-8, with men having more than women (chi-square = 15.349, 7 d.f., p<.05). Analyses of the 4 most frequent conditions were conducted. We found 59 subjects with a diagnosis of myocardial infarction (45 men; 14 women), but only 4 concordant twinpairs; of those 2 brothers preceded their sister in year of diagnosis. We found 72 cases of congestive heart failure (43 men; 29 women), but only 12 concordant twinpairs; in half of those cases, the brother preceded his sister. We found 61 cases of stroke (34 men; 27 women), but only 12 concordant twinpairs; in 5 cases the brother preceded his sister. We found 181 subjects with arterial hypertension (77 men; 104 women), and 66 concordant twinpairs; in 31 of those twinpairs, the brother preceded his sister, and in 35 the sister preceded her brother. Additional pattern analyses will be presented that describe the arrays of cardiovascular co-morbidities and their year of diagnosis within twinpairs and the whole sample.

Benefits and Learning Objectives

To present pattern analyses of cardiovascular conditions in an unlike-sex twin sample

Identifiers
urn:nbn:se:hj:diva-4693 (URN)
Available from: 2007-11-23 Created: 2007-11-23Bibliographically approved
Dahl, A., Berg, S. & Nilsson, S. (2007). Identification of dementia in epidemiological research: A study on the usefulness of various data sources. Aging Clinical and Experimental Research, 19(5), 381-389
Open this publication in new window or tab >>Identification of dementia in epidemiological research: A study on the usefulness of various data sources
2007 (English)In: Aging Clinical and Experimental Research, ISSN 1594-0667, E-ISSN 1720-8319, Vol. 19, no 5, p. 381-389Article in journal (Refereed) Published
Abstract [en]

Background and aims: Prevalence and incidence ratios of dementia in epidemiological studies vary according to the data source used. Medical records, cognitive tests, and registry information are sources frequently used to differentiate dementia from normal aging. The aim of the present study was to compare the identification of dementia from these different sources with that from consensus diagnosis. 

Methods: 498 elderly people (age range 70–81 at baseline) enrolled in a Swedish population-based longitudinal twin study (Gender) were evaluated on physical and mental health and interviewed for their socio-demographic background three times during an eight-year period. Reviews of medical records and the Swedish Discharge Registry (DR) were conducted. The 10th percentile was used to differentiate between dementia and non-dementia in all cognitive tests. Scores of 24 or below on the Mini-Mental State Examination (MMSE) (range 1–30) indicated dementia. A consensus conference diagnosed dementia on the basis of total information. The consensus diagnosis was used as the gold standard. 

Results: MMSE scores (sensitivity 64%, specificity 96%, kappa 0.65) and the review of medical records (sensitivity 57%, specificity 99%, kappa 0.65) were good sources for dementia identification. The precision of medical records increased when recordings of cognitive impairment were included (sensitivity 83%, specificity 98%, kappa 0.84). The discharge registry had low sensitivity (26%) and kappa coefficient (0.31). 

Conclusions: The present study shows that both review of medical records and MMSE scores are good although not perfect identifiers of dementia. The discharge registry is an uncertain source of dementia identification.

Place, publisher, year, edition, pages
Springer, 2007
Keywords
Cognitive tests; consensus; dementia; diagnosis; medical records
National Category
Other Social Sciences not elsewhere specified
Identifiers
urn:nbn:se:hj:diva-4280 (URN)10.1007/BF03324718 (DOI)000251732600007 ()18007116 (PubMedID)2-s2.0-37349072462 (Scopus ID)
Available from: 2007-11-02 Created: 2007-11-02 Last updated: 2019-04-09Bibliographically approved
Nilsson, S., Takkinen, S., Berg, S., Johansson, B., Mellander, A. & Lindblad, U. (2007). Low systolic blood pressure is associated with impaired cognitive function in the oldest old: Longitudinal observations in a population-based sample 80 years and older. Aging Clinical and Experimental Research, 19(1), 41-47
Open this publication in new window or tab >>Low systolic blood pressure is associated with impaired cognitive function in the oldest old: Longitudinal observations in a population-based sample 80 years and older
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2007 (English)In: Aging Clinical and Experimental Research, ISSN 1594-0667, E-ISSN 1720-8319, Vol. 19, no 1, p. 41-47Article in journal (Refereed) Published
National Category
Other Social Sciences not elsewhere specified
Identifiers
urn:nbn:se:hj:diva-2985 (URN)
Available from: 2007-10-30 Created: 2007-10-30 Last updated: 2017-12-12Bibliographically approved
Nilsson, S. E. (2006). Anders Andersson: bortglömd medlem av Svenska akademien.. Läkartidningen, 103(37), 2678-2679
Open this publication in new window or tab >>Anders Andersson: bortglömd medlem av Svenska akademien.
2006 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 103, no 37, p. 2678-2679Article in journal (Other (popular science, discussion, etc.)) Published
Identifiers
urn:nbn:se:hj:diva-3935 (URN)
Available from: 2007-10-30 Created: 2007-10-30 Last updated: 2017-12-12Bibliographically approved
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